⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionaldehyde SCHEMBL7524407 | 0.90 | — | — | |
| Acetone SCHEMBL3205797 | 0.86 | — | — | |
| Propionaldehyde SCHEMBL16792801 | 0.84 | ALDH1A1 (0.56) | — | |
| Acetic Acid SCHEMBL10501034 | 0.83 | — | — | |
| Propionaldehyde SCHEMBL28298257 | 0.82 | — | — | |
| Butanone SCHEMBL11582162 | 0.80 | — | — | |
| Acetic Acid SCHEMBL28096565 | 0.80 | — | — | |
| Butanal SCHEMBL27351305 | 0.79 | — | — | |
| Propionaldehyde SCHEMBL14746311 | 0.79 | ALDH1A1 (0.69) | — | |
| Propionaldehyde SCHEMBL28312820 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478278-B1 | METHOD OF DETERMINING ACUTE OR NON-HEALING WOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2024-06-12 | — | — | EP | disclosed |
| US-11234945-B2 | Wound healing composition | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-02-01 | — | — | US | disclosed |
| US-20190262282-A1 | A WOUND HEALING COMPOSITION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-08-29 | — | — | US | disclosed |
| EP-3478278-A1 | A WOUND HEALING COMPOSITION | Agency for Science, Technology and Research (SG) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018004467-A1 | A WOUND HEALING COMPOSITION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-01-04 | — | — | WO | disclosed |
| EP-1357881-A4 | INHIBITORS OF SPERMIDINE SYNTHASE FOR THE TREATMENT OF OSTEOARTHRITIS AND CARTILAGE REHABILITATION | QUARK PHARMACEUTICALS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| US-20070280946-A1 | Antibody to 5' -Deoxy-5' - Methylthioadenosine And Uses Thereof | QUARK PHARMACUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20040229886-A1 | Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation | QUARK BIOTECH, INC. & SHIONOGI CO., LTD. | 2004-11-18 | — | — | US | disclosed |
| US-6696454-B2 | ADMINISTERING AN INHIBITOR OF SPERMIDINE BIOSYNTHESIS; PREFERRED ARE DCHA (DICYCLOHEXYLAMINE), ADODATO, AND TRANS-4-METHYLCYCLOHEXYLAMINE (4MCHA) | QUARK BIOTECH, INC. | 2004-02-24 | — | — | US | disclosed |
| EP-1357881-A2 | INHIBITORS OF SPERMIDINE SYNTHASE FOR THE TREATMENT OF OSTEOARTHRITIS AND CARTILAGE REHABILITATION | Quark Biotech, Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| US-20020160978-A1 | Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation | QUARK PHARMACEUTICALS, INC. | 2002-10-31 | — | — | US | disclosed |
| WO-2002058623-A2 | INHIBITORS OF SPERMIDINE SYNTHASE FOR THE TREATMENT OF OSTEOARTHRITIS AND CARTILAGE REHABILITATION | QUARK BIOTECH, INC. (US) | 2002-08-01 | — | — | WO | disclosed |