Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178309 | 0.94 | PTGS1 (0.45) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4181081 | 0.93 | PTGS1 (0.47) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13875599 | 0.86 | KDM4E (0.46) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4187879 | 0.86 | MAPT (0.38) | PTGS1KCNJ11P2RX1MAPTMEN1 | |
| SCHEMBL404470 | 0.84 | PTGS1 (0.51) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4189764 | 0.83 | PTGS1 (0.46) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28496399 | 0.83 | PTGS1 (0.53) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13875600 | 0.80 | KDM4E (0.45) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4182215 | 0.80 | PTGS1 (0.47) | PTGS1KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4175359 | 0.78 | MAPT (0.39) | PTGS1KCNJ11P2RX1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-1916236-A1 | AMIDE DERIVATIVE, PESTICIDE CONTAINING SUCH COMPOUND AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | CYP2E1, GSTA1, CYP2S1 | PTGS1 1316/4885KDM4E 1117/4885ALDH1A1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.