Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.61 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639351 | 0.98 | TAAR1 (0.59) | TAAR1ERN1ESR1ESR2LPL | |
| SCHEMBL14542115 | 0.88 | TAAR1 (0.59) | TAAR1ERN1ESR1ESR2LPL | |
| SCHEMBL394300 | 0.87 | TAAR1 (0.76) | TAAR1ERN1LPLLIPGPOLB | |
| SCHEMBL30487922 | 0.85 | TAAR1 (0.73) | TAAR1ERN1LPLLIPGPOLB | |
| SCHEMBL244155 | 0.79 | — | — | |
| SCHEMBL6067949 | 0.79 | ERN1 (0.49) | TAAR1ERN1ESR1ESR2POLB | |
| SCHEMBL3468357 | 0.79 | TAAR1 (0.41) | TAAR1ERN1ESR1ESR2LPL | |
| SCHEMBL7404185 | 0.78 | TAAR1 (0.64) | TAAR1LPLLIPGPOLBKDM4E | |
| SCHEMBL28323221 | 0.77 | TAAR1 (0.62) | TAAR1ERN1LPLLIPGPOLB | |
| SCHEMBL162083 | 0.77 | TAAR1 (0.62) | TAAR1LPLLIPGPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582949-B | Oxygen bridge bicyclo- [2.2.1] -heptene compound containing different covalent warhead structures and preparation and application thereof | 武汉大学 | 2023-06-30 | — | — | CN | claimed |
| CN-113582949-A | Oxygen-bridged bicyclo- [2.2.1] -heptene compound containing different covalent warhead structures and preparation and application thereof | 武汉大学 | 2021-11-02 | — | — | CN | claimed |
| CN-108864127-B | Oxidobicycloheptene sulfonamide compound with different alkyl chain lengths as well as preparation method and application thereof | 武汉大学 | 2020-06-23 | — | — | CN | claimed |
| CN-107188896-B | Oxocycloheptene compound containing resveratrol group and preparation and use method thereof | 苏州楚凯药业有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-109942595-A | Oxygen bridge containing different functionalities side-chain structure is bicyclic-[2.2.1]-heptan vinyl compound and its preparation and application | 武汉大学 | 2019-06-28 | — | — | CN | claimed |
| CN-108864127-A | A kind of oxygen bridge double-heptene sulfamide compound and the preparation method and application thereof containing different alkyl chain lengths | 武汉大学 | 2018-11-23 | — | — | CN | claimed |
| CN-105111244-B | Bicyclic [2.2.1] vinyl compound in heptan of ferrocene oxygen bridge | 铱诺(武汉)药业有限公司 | 2018-02-09 | — | — | CN | claimed |
| CN-103596943-B | Hydantoin derivatives useful as KV3 inhibitors | 奥蒂福尼疗法有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-100522128-C | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2009-08-05 | — | — | CN | claimed |
| CN-115850294-B | Oxygen bridge bicyclo- [2.2.1] -heptene compound containing selenocyano side chain, and preparation method and application thereof | 武汉大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115557965-B | PROTACs compound for dual targeting degradation of estrogen receptor alpha and aromatizing enzyme and application thereof | 武汉大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-113582949-B | Oxygen bridge bicyclo- [2.2.1] -heptene compound containing different covalent warhead structures and preparation and application thereof | 武汉大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114560867-B | Oxygen bridge bicycloheptene sulfonate compound containing five-membered nitrogen heterocycle and application thereof in preparation of breast cancer resisting drugs | 武汉大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113773283-B | Oxidobicycloheptene sulfonamide compound containing hydrophobic label and application thereof | 武汉大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-1709241-A | Intravenous injection stable concertrated clear solution containing rifamycin after dilution | SUZHOU CHANGZHENG XINKAI PHARM (CN) | 2005-12-21 | — | — | CN | disclosed |
| US-4857539-A | Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents | STERLING DRUG INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0207453-A2 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4431831-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | RIKER LABORATORIES, INC. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0080356-A2 | Substituted furans | RIKER LABORATORIES, INC. (US) | 1983-06-01 | — | — | EP | disclosed |
| US-4357345-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1982-11-02 | — | — | US | disclosed |