Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162083 | 0.95 | TAAR1 (0.62) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| SCHEMBL11073018 | 0.92 | TAAR1 (0.60) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8104290 | 0.92 | TAAR1 (0.60) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| SCHEMBL30487922 | 0.92 | TAAR1 (0.73) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| SCHEMBL394300 | 0.89 | TAAR1 (0.76) | TAAR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL244155 | 0.87 | — | — | |
| SCHEMBL28323221 | 0.84 | TAAR1 (0.62) | TAAR1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL27761661 | 0.84 | KEAP1 (0.59) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| SCHEMBL12230533 | 0.83 | TAAR1 (0.52) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E | |
| SCHEMBL20324154 | 0.83 | TAAR1 (0.52) | TAAR1PIK3R1PIK3CAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516880-B | Method for synthesizing furo [2,3-b ] quinoxaline derivative | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114516880-A | Novel method for synthesizing furo [2,3-b ] quinoxaline derivative | 桂林理工大学 | 2022-05-20 | — | — | CN | disclosed |
| US-10662206-B2 | Method for preparing silane derivatives from furan derivatives in presence of borane catalyst | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-05-26 | — | — | US | disclosed |
| US-20190263840-A1 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-08-29 | — | — | US | disclosed |
| WO-2017204554-A2 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | 기초과학연구원 | 2017-11-30 | — | — | WO | disclosed |
| US-6495699-B2 | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | AGOURON PHARMACEUTICALS INC. | 2002-12-17 | — | — | US | disclosed |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | BENDER STEVEN L (US) | 2002-02-14 | — | — | US | disclosed |
| US-6306892-B1 | ENZYME INHIBITORS HETEROCYCLIC AMIDES | AGOURON PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6174915-B1 | FOR TREATING MAMMALIAN DISEASE CONDITION MEDIATED BY METALLOPROTEINASE ACTIVITY | AGOURON PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |
| US-6008243-A | AN ENZYME INHIBITOR FOR PREVENTING THE DEGRADATION AND REMODELING OF CONNECTIVE TISSUES | AGOURON PHARMACEUTICALS, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0937042-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998017643-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1998-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662206-B2 | Method for preparing silane derivatives from furan derivatives in presence of borane catalyst | PFAS, HPD, FDPS | TAAR1 4244/4885PIK3R1 3376/4885PIK3CA 1152/4885 |
| US-20190263840-A1 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | PFAS, HPD, FDPS | TAAR1 4244/4885PIK3R1 3376/4885PIK3CA 1152/4885 |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | MMP9, MMP2, MMP3 | TAAR1 4474/4885PIK3R1 2592/4885PIK3CA 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.