SCHEMBL4192033

SCHEMBL4192033

CCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCC)NC(=O)CN

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.56
PLA2G2C Q5R387 3/20 0.56
PLA2G10 O15496 2/20 0.46
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
RRM1 P23921 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
FAAH O00519 2/20 0.44
MAPK1 P28482 1/20 0.44
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
SIRT6 Q8N6T7 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.42
ASAH1 Q13510 1/20 0.41
SLC6A5 Q9Y345 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197726 0.93 PLA2G2C (0.50) DNM1PLA2G2CPLA2G10GNAI3GNAO1
SCHEMBL6888279 0.88 PLA2G2C (0.49) DNM1PLA2G2CPLA2G10GNAI3GNAO1
SCHEMBL1258599 0.84 PLA2G2C (0.64) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL22369854 0.83 FAAH (0.47) DNM1GNAI3GNAO1GNAI1MEN1
SCHEMBL25067268 0.82 PLA2G2C (0.77) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL6943359 0.82 PLA2G2C (0.67) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL31318140 0.82 PLA2G2C (0.77) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL31364557 0.82 PLA2G2C (0.77) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL30679514 0.82 PLA2G2C (0.77) DNM1PLA2G2CPLA2G10MEN1KMT2A
SCHEMBL27753924 0.82 PLA2G2C (0.77) DNM1PLA2G2CPLA2G10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2015780-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2009-01-21 EP claimed
WO-2007130073-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2007-11-15 WO claimed
CN-118271422-A Transfection complexes and methods of use thereof 分子传递有限公司 2024-07-02 CN disclosed