Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.84 |
| ▸ | NOS2 | P35228 | 9/20 | 0.83 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.82 |
| ▸ | USP7 | Q93009 | 2/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | STAT3 | P40763 | 1/20 | 0.82 |
| ▸ | CCR6 | P51684 | 1/20 | 0.71 |
| ▸ | RORC | P51449 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489259 | 1.00 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL13569164 | 1.00 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL13569167 | 1.00 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL7717247 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL22428638 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL15021390 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL91616 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL19635891 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL13499871 | 0.93 | MBOAT4 (0.84) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 | |
| SCHEMBL22964830 | 0.93 | MBOAT4 (0.82) | MBOAT4NOS2KEAP1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146216-A2 | ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID | REATA PHARMACEUTICALS. INC. (US) | 2009-12-03 | — | — | WO | disclosed |