Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967650 | 0.99 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3479821 | 0.98 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3480051 | 0.98 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3480006 | 0.92 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3479709 | 0.91 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3480040 | 0.88 | MAPK9 (0.52) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL4969266 | 0.86 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3479946 | 0.85 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL3480185 | 0.84 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2ADRD2 | |
| SCHEMBL3480069 | 0.84 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |