Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479709 | 0.94 | MAPK9 (0.54) | MAPK9MAPK10KMT2AMEN1OPRM1 | |
| SCHEMBL3480137 | 0.94 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL3480051 | 0.88 | MAPK9 (0.54) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL3479821 | 0.88 | MAPK9 (0.54) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL4967650 | 0.87 | MAPK9 (0.53) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL3480185 | 0.87 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL3479946 | 0.86 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1POLB | |
| SCHEMBL3480006 | 0.86 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL4192955 | 0.86 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1DRD2 | |
| SCHEMBL3480040 | 0.85 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |