SCHEMBL4194150

SCHEMBL4194150

CC(=O)Oc1ccc2c(C(C)C)c(OC(C)=O)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.48
KDM4E B2RXH2 6/20 0.45
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
GAA P10253 6/20 0.42
GLA P06280 5/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KMT2A Q03164 1/20 0.42
FLT3 P36888 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
HSD17B10 Q99714 2/20 0.41
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4186794 0.81 KDM4E (0.50) NCEH1KDM4ECA12CA9GAA
SCHEMBL9510673 0.79 NCEH1 (0.51) NCEH1KDM4ECA12CA9GAA
SCHEMBL9506861 0.78 TUBB4A (0.50) KDM4ECA12CA9GAAGLA
SCHEMBL10433173 0.78 KDM4E (0.54) KDM4ECA12CA9GAAGLA
SCHEMBL5352558 0.77 CA12 (0.61) KDM4ECA12CA9GAAGLA
SCHEMBL29705954 0.77 CA12 (0.61) KDM4ECA12CA9GAAGLA
SCHEMBL3974361 0.77 CA12 (0.65) KDM4ECA12CA9GAAGLA
SCHEMBL30595409 0.77 CA12 (0.65) KDM4ECA12CA9GAAGLA
SCHEMBL487221 0.76 KDM4E (0.54) KDM4ECA12CA9GAAGLA
SCHEMBL9476254 0.75 KDM4E (0.50) KDM4ECA12CA9GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601775-B2 Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica NIPPON SHOKUBAI CO., LTD. (JP) 2009-10-13 US disclosed
US-20060167164-A1 Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica NIPPON SHOKUBAI CO., LTD. (JP) 2006-07-27 US disclosed
CN-1656177-A Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica NIPPON CATALYTIC CHEM IND (JP) 2005-08-17 CN disclosed
EP-1507829-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA Nippon Shokubai Co., Ltd. (JP) 2005-02-23 EP disclosed
WO-2003099934-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA NIPPON SHOKUBAI CO., LTD. (JP) 2003-12-04 WO disclosed