Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 4/20 | 0.50 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804438 | 1.00 | BCHE (0.55) | BCHETK1RNASE1LMNATSHR | |
| SCHEMBL13948027 | 0.91 | BCHE (0.52) | BCHETK1LMNAALBPKM | |
| SCHEMBL12969489 | 0.91 | BCHE (0.52) | BCHETK1LMNAALBPKM | |
| SCHEMBL9819384 | 0.91 | BCHE (0.52) | BCHETK1LMNAALBPKM | |
| SCHEMBL24548453 | 0.89 | BCHE (0.52) | BCHETK1ABCG2ABCB1 | |
| SCHEMBL9355402 | 0.88 | ABCG2 (0.52) | BCHETK1ABCG2ABCB1 | |
| SCHEMBL27815893 | 0.88 | ABCG2 (0.54) | BCHETK1RNASE1ABCG2ABCB1 | |
| SCHEMBL13497253 | 0.87 | BCHE (0.52) | BCHETK1ABCG2ABCB1 | |
| SCHEMBL22992494 | 0.87 | RNASE1 (0.60) | BCHETK1RNASE1ABCG2ABCB1 | |
| SCHEMBL5054200 | 0.87 | RNASE1 (0.60) | BCHETK1RNASE1ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608402-B2 | DNA methylation specific signal amplification | LI WEIWEI | 2009-10-27 | — | — | US | disclosed |
| US-20090181373-A1 | DNA methylation specific signal amplification | LI WEIWEI | 2009-07-16 | — | — | US | disclosed |