SCHEMBL4194847

SCHEMBL4194847

N#CC(CC(=O)O)/N=N/C(C#N)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.30
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4194849 1.00 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL887793 0.76 TET2 (0.39) LMNATSHRFOLH1
SCHEMBL887792 0.76 TET2 (0.39) LMNATSHRFOLH1
SCHEMBL129689 0.73 GSTK1 (0.44) SLC22A6GABRR1LMNATSHRFOLH1
SCHEMBL5821426 0.70 SLC22A6 (0.43) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL2146570 0.70
Ammonia Solution, Strong SCHEMBL28654999 0.69 TDP1 (0.46) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL8148889 0.69 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
SCHEMBL5815555 0.69 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
SCHEMBL8148891 0.69 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1642934-B1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL IND LTD (JP) 2012-12-12 EP disclosed
US-7619037-B2 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-17 US disclosed
US-20060281860-A1 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-14 US disclosed
EP-1642934-A1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-05 EP disclosed