GSTK1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL240041	0.65	2/20
SCHEMBL994189	0.63	2/20
SCHEMBL2181037	0.63	2/20
SCHEMBL541769	0.61	2/20
SCHEMBL380054	0.59	2/20
SCHEMBL754548	0.58	2/20
SCHEMBL289697	0.56	2/20
SCHEMBL2181858	0.56	2/20
Dihydrolipoic Acid (SCHEMBL19773)	0.55	2/20
Dihydrolipoic Acid (SCHEMBL618576)	0.55	2/20
Dihydrolipoic Acid (SCHEMBL867951)	0.55	2/20
Dihydrolipoic Acid (SCHEMBL1115003)	0.55	2/20
SCHEMBL1198436	0.55	2/20
SCHEMBL1232654	0.55	2/20
SCHEMBL1487668	0.55	2/20
SCHEMBL39651	0.54	2/20
SCHEMBL2141548	0.54	2/20
SCHEMBL287721	0.54	2/20
SCHEMBL289225	0.54	2/20
SCHEMBL527023	0.54	2/20

Clinical trials — most relevant to GSTK1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure	PHASE2	COMPLETED
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS	PHASE1/PHASE2	COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy	PHASE2	RECRUITING
Prevent Cardiac Surgery Associated AKI Trial	PHASE2	RECRUITING
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD	PHASE2	COMPLETED
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism	PHASE2	ACTIVE_NOT_RECRUITING
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers	PHASE2	RECRUITING
Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria	PHASE1/PHASE2	SUSPENDED
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels	PHASE1	COMPLETED
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC)	PHASE1	UNKNOWN
Broccoli and Vascular Health Study	nan	COMPLETED
Mechanisms of Response to Diesel Exhaust in Subjects With Asthma	nan	WITHDRAWN
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE)	nan	COMPLETED
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma	nan	COMPLETED
Usefulness of Alpha-GST in Liver Transplantation	nan	UNKNOWN
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Muscle Wasting in Cancer (MWIC)	nan	COMPLETED
Factors in Childhood Lung Susceptibility to Pollution	nan	COMPLETED
ADAPT: Efficacy of a Dietary Supplement During and After Exercise	nan	COMPLETED
Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance	nan	COMPLETED
Cancer and Hearing Loss Related in Children	nan	COMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease	nan	COMPLETED
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers	nan	COMPLETED
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans	nan	COMPLETED
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer	nan	COMPLETED
Tecfidera Diffusion Tensor Imaging	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a GSTK1 binder may also engage these)

Protein	Name	Similarity
P24473	—	0.962	P24473 →
Q9DCM2	—	0.961	Q9DCM2 →
P20135	—	0.943	P20135 →
Q6AXV9	—	0.941	Q6AXV9 →
Q8R4N0	—	0.938	Q8R4N0 →
P47802	—	0.936	P47802 →
Q9QZ08	—	0.936	Q9QZ08 →
Q5I0K3	—	0.935	Q5I0K3 →
Q9H4Y5	—	0.935	Q9H4Y5 →
Q9H4I8	—	0.934	Q9H4I8 →
Q28DS0	—	0.933	Q28DS0 →
Q99L20	—	0.933	Q99L20 →
Q8K183	—	0.932	Q8K183 →
B1WC37	—	0.931	B1WC37 →
P30711	—	0.931	P30711 →
Q9UJ70	—	0.931	Q9UJ70 →
Q5R5F8	—	0.931	Q5R5F8 →
Q5U4X8	—	0.930	Q5U4X8 →
Q9D7I5	—	0.930	Q9D7I5 →
Q8N0X4	—	0.930	Q8N0X4 →
Q8K2Q2	—	0.930	Q8K2Q2 →
Q4R4U1	—	0.930	Q4R4U1 →
BPHL	Serine hydrolase BPHL	0.929	landscape →
Q96JC1	—	0.929	Q96JC1 →
Q5RCW2	—	0.929	Q5RCW2 →
Q8JGT5	—	0.929	Q8JGT5 →
Q05B63	—	0.928	Q05B63 →
Q923S8	—	0.928	Q923S8 →
Q9DAT5	—	0.928	Q9DAT5 →
Q5RA57	—	0.928	Q5RA57 →