Mycophenolate Mofetil

Mycophenolate Mofetil

SCHEMBL4195

COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)OCCN1CCOCC1)C(=O)OC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

IMPDH1IMPDH2

The experimentally established mechanism targets of Mycophenolate Mofetil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 known ✓ P12268 19/20 0.70
IMPDH1 known ✓ P20839 14/20 0.70
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
HPGD P15428 2/20 1.00
ABCC4 O15439 1/20 1.00
NR1I2 O75469 1/20 1.00
ABCB11 O95342 1/20 1.00
SLC6A4 P31645 1/20 1.00
KCNH2 Q12809 1/20 1.00
PDE3A Q14432 1/20 1.00
KDM4E B2RXH2 1/20 0.66
CYP1A2 P05177 1/20 0.66
CYP3A4 P08684 1/20 0.66
UGT2B7 P16662 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
HSD17B10 Q99714 1/20 0.66
HDAC3 O15379 2/20 0.63
HDAC4 P56524 2/20 0.63
HDAC1 Q13547 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mycophenolate Mofetil SCHEMBL29645056 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL29378681 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL28390 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL29571382 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL218782 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL23581135 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL10262894 1.00 ALDH1A1 (1.00) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL1235420 0.99 ALDH1A1 (0.98) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL2257852 0.99 ALDH1A1 (0.98) ALDH1A1LMNAHPGDABCC4NR1I2
Mycophenolate Mofetil SCHEMBL3016437 0.99 ALDH1A1 (0.98) ALDH1A1LMNAHPGDABCC4NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 54614 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144816-A1 COMPOSITIONS AND METHODS FOR TREATING DEMENTIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-28 US claimed
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
EP-4749286-A2 METHOD OF ASSESSING RISK OF PML Biogen MA Inc. (US) 2026-05-27 EP claimed
US-12636319-B2 Pharmaceutical composition for preventing or treating atopic disease containing Akkermansia muciniphila strain ENTEROBIOME INC. (KR) 2026-05-26 US claimed
US-20260141455-A1 LOCATION BASED DATABASE SYSTEM DASHBOARDS EXPRESS SCRIPTS STRATEGIC DEV INC (US) 2026-05-21 US claimed
WO-2026107075-A1 METHODS OF TREATING MULTIPLE SCLEROSIS WITH CD19-CD20 DUAL CAR-T CELLS GENENTECH, INC. (US) 2026-05-21 WO claimed
WO-2026104987-A1 REMIBRUTINIB FOR USE IN THE TREATMENT OF MYASTHENIA GRAVIS NOVARTIS AG (CH) 2026-05-21 WO claimed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
WO-2026103922-A1 CHIMERIC SHUTTLING RECEPTOR 深圳市湾岛细胞科技有限公司 2026-05-21 WO claimed
EP-0697866-A1 HIGH DOSE FORMULATIONS SYNTEX (U.S.A.) INC. (US) 1996-02-28 EP claimed
WO-1996002004-A1 IMMUNOASSAY FOR MYCOPHENOLIC ACID BEHRINGWERKE AG (DE) 1996-01-25 WO claimed
US-5455045-A Active agent of mycophenolate mofetil and mycophenolic acid; liquefying by melting, cooling, filling into dosage form; oral administration; Penicillium; immunosuppressant drugs SYNTEX (U.S.A.) INC. (US) 1995-10-03 US claimed
EP-0670724-A1 USE OF MYCOPHENOLIC ACID, MYCOPHENOLATE MOFETIL OR DERIVATE THEREOF TO INHIBIT STENOSIS SYNTEX (U.S.A.) INC. (US) 1995-09-13 EP claimed
EP-0649422-A1 DIRECT ESTERIFICATION OF MYCOPHENOLIC ACID. SYNTEX INC (US) 1995-04-26 EP claimed
WO-1995009626-A1 MYCOPHENOLATE MOFETIL HIGH DOSE ORAL SUSPENSIONS SYNTEX (U.S.A.) INC. (US) 1995-04-13 WO claimed
WO-1994026266-A1 HIGH DOSE FORMULATIONS SYNTEX (U.S.A.) INC. (US) 1994-11-24 WO claimed
WO-1994012184-A1 USE OF MYCOPHENOLIC ACID, MYCOPHENOLATE MOFETIL OR DERIVATE THEREOF TO INHIBIT STENOSIS SYNTEX (U.S.A.) INC. (US) 1994-06-09 WO claimed
WO-1994001427-A1 DIRECT ESTERIFICATION OF MYCOPHENOLIC ACID SYNTEX (U.S.A.) INC. (US) 1994-01-20 WO claimed
US-5247083-A Direct esterification of mycophenolic acid SYNTEX (U.S.A.) INC. (US) 1993-09-21 US claimed