SCHEMBL4196332

SCHEMBL4196332

CC1c2ccc3ncccc3c2CCN1C(=O)c1cc2ccc(Br)cn2n1.CC1c2ccc3ncccc3c2CCN1C(=O)c1cc2ccc(Cl)cn2n1.Cc1nc2c3c(ccc2o1)C(C)N(C(=O)c1cc2ccc(Br)cn2n1)CC3.Cc1nc2c3c(ccc2o1)C(C)N(C(=O)c1cc2ccc(Cl)cn2n1)CC3.Cc1nc2c3c(ccc2s1)C(C)N(C(=O)c1cc2ccc(Br)cn2n1)CC3

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3821046 0.82 GRM5 (0.37)
SCHEMBL3820245 0.82 GRM5 (0.37)
SCHEMBL4076622 0.82 GRM5 (0.44)
SCHEMBL3817661 0.81 NPSR1 (0.33)
SCHEMBL3816593 0.81 GRM5 (0.38) FNTAFNTB
SCHEMBL3821118 0.81 FNTA (0.37) FNTAFNTB
SCHEMBL3811252 0.81 HTT (0.33)
SCHEMBL1009122 0.73 GRM5 (0.54)
SCHEMBL1009988 0.73 GRM5 (0.54)
SCHEMBL1012852 0.73 GRM5 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009095253-A1 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS MERZ PHARMA GMBH & CO. KGAA (DE) 2009-08-06 WO disclosed