⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551749 | 0.76 | — | — | |
| SCHEMBL2343477 | 0.75 | — | — | |
| SCHEMBL22171228 | 0.75 | — | — | |
| SCHEMBL13057193 | 0.75 | — | — | |
| SCHEMBL13196610 | 0.75 | — | — | |
| SCHEMBL3540533 | 0.73 | TLR4 (0.30) | — | |
| SCHEMBL13440235 | 0.71 | — | — | |
| SCHEMBL19321813 | 0.71 | — | — | |
| SCHEMBL5209248 | 0.71 | — | — | |
| SCHEMBL19321816 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331705-A1 | Fused Imidazole Derivatives as AHR Antagonists | SENDA BIOSCIENCES, INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO HEALTH, INC. | 2023-08-03 | — | — | US | disclosed |
| CN-107922366-A | Pyruvate dehydrogenase kinase inhibitor and application thereof | 华东理工大学 | 2018-04-17 | — | — | CN | disclosed |
| US-8203002-B2 | Intermediates for the preparation of pramipexole | DIPHARMA S.P.A. (IT) | 2012-06-19 | — | — | US | disclosed |
| US-20100222595-A1 | INTERMEDIATES FOR THE PREPARATION OF PRAMIPEXOLE | DIPHARMA S.P.A. (IT) | 2010-09-02 | — | — | US | disclosed |
| US-7741490-B2 | Intermediates for the preparation of pramipexole | DIPHARMA S.P.A. (IT) | 2010-06-22 | — | — | US | disclosed |
| EP-1517911-B1 | TUMOUR-INHIBITING PLATINUM (II) OXALATE COMPLEXES | KEPPLER PROF DR DR BERNHARD K (AT) | 2009-07-29 | — | — | EP | disclosed |
| US-20070191439-A1 | Intermediates for the preparation of pramipexole | DIPHARMA S.P.A. (IT) | 2007-08-16 | — | — | US | disclosed |
| US-7057059-B2 | Tumor-inhibiting platinum (II) oxalate complexes | FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH (DE) | 2006-06-06 | — | — | US | disclosed |
| US-20050143455-A1 | Tumor-inhibiting platinum (II) oxalate complexes | FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH | 2005-06-30 | — | — | US | disclosed |
| EP-1517911-A1 | TUMOUR-INHIBITING PLATINUM (II) OXALATE COMPLEXES | Faustus Forschungs Cie. Translational Cancer Research GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003106469-A1 | TUMOUR-INHIBITING PLATINUM (II) OXALATE COMPLEXES | FAUSTUS FORSCHUNGS CIE. TRANSLATIONAL CANCER RESEARCH GMBH (DE) | 2003-12-24 | — | — | WO | disclosed |
| US-4535081-A | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | PFIZER INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4423048-A | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4414388-A | ANTIALLERGENS, ANTIULCER AGENTS | PFIZER INC. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-3954981-A | Triazolocycloalkylhydrothiadiazine derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |