Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61962 | 0.97 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL10864095 | 0.90 | TSHR (0.36) | TSHRALDH1A1TDP1 | |
| SCHEMBL444876 | 0.89 | — | — | |
| SCHEMBL5405071 | 0.78 | — | — | |
| SCHEMBL5419424 | 0.78 | — | — | |
| SCHEMBL230592 | 0.77 | — | — | |
| SCHEMBL399613 | 0.76 | — | — | |
| SCHEMBL1040099 | 0.76 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL16834811 | 0.76 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL3268203 | 0.76 | TSHR (0.44) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428829-B1 | PROCESS FOR PREPARATION OF THIOCYANATO-BEARING ORGANOALKOXYSILANES | DOW CORNING TORAY CO LTD (JP) | 2009-02-18 | — | — | EP | disclosed |
| WO-2005103061-A1 | METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS | DOW CORNING TORAY CO., LTD. (JP) | 2005-11-03 | — | — | WO | disclosed |
| US-6867319-B2 | Process for preparation of thiocyanato-bearing organoalkoxysilanes | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-1234830-B1 | Method of preparing an organosilicon compound containing a methacryloxy functional group | DOW CORNING TORAY SILICONE (JP) | 2005-01-19 | — | — | EP | disclosed |
| US-20040210075-A1 | Process for preparation of thiocyanato-bearing organoalkoxysilanes | DOW CORNING TORAY SILICONE COMPANY LIMITED (JP) | 2004-10-21 | — | — | US | disclosed |
| EP-1428829-A1 | PROCESS FOR PREPARATION OF THIOCYANATO−BEARING ORGANOALKOXYSILANES | Dow Corning Toray Silicone Company, Ltd. (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6448427-B1 | REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1234830-A2 | Method of preparing an organosilicon compound containing a methacryloxy functional group | Dow Corning Toray Silicone Co., Ltd. (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-20020115878-A1 | METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP | DOW TORAY CO., LTD. (JP) | 2002-08-22 | — | — | US | disclosed |
| US-5117027-A | Esterification | HULS AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4946977-A | CATALYTIC REACTING ALKALI (METH)ACRYLATE WITH HALOGEN ALKYLALKOXYSILANE | HUELS TROISDORF AG (DE) | 1990-08-07 | — | — | US | disclosed |