Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.71 |
| ▸ | DDO | Q99489 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362300 | 0.83 | DAO (1.00) | DAODDOCA12CA9HRH4 | |
| SCHEMBL12970395 | 0.83 | DAO (0.65) | DAODDOCA12CA9HRH4 | |
| SCHEMBL31378708 | 0.83 | DAO (0.65) | DAODDOCA12CA9HRH4 | |
| SCHEMBL3316092 | 0.83 | DAO (0.65) | DAODDOCA12CA9HRH4 | |
| SCHEMBL4069728 | 0.80 | DAO (0.61) | DAODDOCA12CA9HRH4 | |
| SCHEMBL1367535 | 0.80 | DAO (0.66) | DAODDOCA12CA9HRH4 | |
| SCHEMBL1534147 | 0.79 | DAO (0.47) | DAODDOHRH4 | |
| SCHEMBL27348185 | 0.79 | DAO (0.64) | DAODDOCA12CA9HRH4 | |
| SCHEMBL31378799 | 0.78 | DAO (0.58) | DAODDOCA12CA9HRH4 | |
| SCHEMBL9432615 | 0.77 | DAO (0.56) | DAODDOCA12CA9HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088345-A1 | NECESSARY AND SUFFICIENT REAGENT SETS FOR CHEMOGENOMIC ANALYSIS | ENTELOS, INC. | 2009-04-02 | — | — | US | disclosed |
| US-20070021918-A1 | Universal gene chip for high throughput chemogenomic analysis | U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2007-01-25 | — | — | US | disclosed |
| US-20060035250-A1 | Necessary and sufficient reagent sets for chemogenomic analysis | U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2006-02-16 | — | — | US | disclosed |
| WO-2006001896-A2 | A UNIVERSAL GENE CHIP FOR HIGH THROUGHPUT CHEMOGENOMIC ANALYSIS | ICONIX PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| WO-2005124650-A2 | SUFFICIENT AND NECESSARY REAGENT SETS FOR CHEMOGENOMIC ANALYSIS | ICONIX PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |