Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.64 |
| ▸ | DDO | Q99489 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367535 | 0.89 | DAO (0.66) | DAODDOCA12CA9HRH4 | |
| SCHEMBL2808417 | 0.85 | DHODH (0.58) | DAODDODHODHCNR2KDM4E | |
| SCHEMBL29415464 | 0.85 | DHODH (0.58) | DAODDODHODHCNR2KDM4E | |
| SCHEMBL9264392 | 0.81 | DAO (0.64) | DAODDOKDM4EGAAALDH1A1 | |
| SCHEMBL27443353 | 0.81 | DAO (0.64) | DAOCA12CA9HRH4DHODH | |
| SCHEMBL4196645 | 0.79 | DAO (0.71) | DAODDOCA12CA9HRH4 | |
| SCHEMBL1145013 | 0.78 | HPGD (0.60) | DAODDOCA12CA9HRH4 | |
| SCHEMBL3362300 | 0.78 | DAO (1.00) | DAODDOCA12CA9HRH4 | |
| SCHEMBL3551666 | 0.77 | KDM4E (0.50) | DAODDODHODHCNR2KDM4E | |
| SCHEMBL21639472 | 0.77 | BRD4 (0.46) | DAODDODHODHCNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041197-C | Substituted 2-chloro-3,4,5-trifluorobenzenes and a process for their preparation | HOECHST AG (DE) | 1998-12-16 | — | — | CN | disclosed |
| CN-1112917-A | Substituted 2-chloro-3,4,5-trifluorobenzenes and a process for their preparation | HOECHST AG (DE) | 1995-12-06 | — | — | CN | disclosed |