Plumieride

Plumieride

SCHEMBL419720

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]2[C@@H]1C=C[C@@]21C=C([C@H](C)O)C(=O)O1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.65
▸ CTDSP1 Q9GZU7 1/20 0.65
▸ MEN1 O00255 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ STAT3 P40763 15/20 0.48
▸ JUN P05412 1/20 0.42
▸ ELANE P08246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gaertneroside SCHEMBL420081 0.89 POLB (0.60) POLBCTDSP1MEN1MAPTKMT2A
Gaertneroside SCHEMBL31179982 0.89 POLB (0.60) POLBCTDSP1MEN1MAPTKMT2A
SCHEMBL29425686 0.88 POLB (0.68) POLBCTDSP1MEN1MAPTKMT2A
Methoxygaertneroside SCHEMBL29425771 0.86 POLB (0.56) POLBCTDSP1MEN1MAPTKMT2A
Methoxygaertneroside SCHEMBL29425775 0.86 POLB (0.56) POLBCTDSP1MEN1MAPTKMT2A
Dehydrogaertneroside SCHEMBL29425897 0.83 POLB (0.62) POLBCTDSP1MEN1MAPTKMT2A
SCHEMBL31239200 0.83 POLB (0.52) POLBCTDSP1MEN1MAPTKMT2A
SCHEMBL31045481 0.83 POLB (0.52) POLBCTDSP1MEN1MAPTKMT2A
Gaertneric Acid SCHEMBL29426009 0.81 POLB (0.49) POLBCTDSP1MEN1MAPTKMT2A
SCHEMBL30833264 0.81 POLB (0.51) POLBCTDSP1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050222053-A1 Iridoid-saccharide compound and method of using same HEALTH RESEARCH, INC. (US) 2005-10-06 — — US claimed
EP-1527783-A1 Iridoid-saccharide compound and method of using same HEALTH RESEARCH, INC. (US) 2005-05-04 — — EP claimed
US-20250031732-A1 FLAVOURING AGENT, COMPOSITION, PRODUCTION METHOD AND USE OF AROMATISING AND FLAVOURING AGENTS BASED ON VANILLA EXTRACT UNIV FEDERAL DO ESTADO DO RIO DE JANEIRO (BR) 2025-01-30 — — US disclosed
CN-119039369-A Preparation method of control of plumeria rubra glycoside 上海诗丹德标准技术服务有限公司 2024-11-29 — — CN disclosed
CN-118271377-A Separation method of iridoid compounds in allamanda cathayensis and application of iridoid compounds in control of pepper blast 中国热带农业科学院香料饮料研究所 2024-07-02 — — CN disclosed
CN-118252838-A Application of plumerianin in preparing medicine for treating or relieving fatty liver 中国科学院上海药物研究所 2024-06-28 — — CN disclosed
WO-2023092212-A1 FLAVOURING AGENT, COMPOSITION, PRODUCTION METHOD AND USE OF AROMATISING AND FLAVOURING AGENTS BASED ON VANILLA EXTRACTS UNIVERSIDADE FEDERAL DO ESTADO DO RIO DE JANEIRO (BR) 2023-06-01 — — WO disclosed
CN-116004326-A Infant washing powder and preparation method thereof 家宝生物科技香港有限公司 2023-04-25 — — CN disclosed
CN-109568332-A Iridoid is preparing the application in analgesic 上海交通大学 2019-04-05 — — CN disclosed
CN-108935806-A A kind of health care tea process 广东省生物工程研究所(广州甘蔗糖业研究所) 2018-12-07 — — CN disclosed
CN-106290686-B The method that HPLC-MS-MS measures WANGLAOJI LIANGCHA component content 广州王老吉药业股份有限公司 2018-08-10 — — CN disclosed
CN-101669526-A Allamanda cathartica extract and application thereof in preparing pesticide ENVIRONMENT AND PLANT PROT INS 2010-03-17 — — CN disclosed
CN-101422419-A Toilet water and manufacture method thereof MASSON GROUP CO LTD (CN) 2009-05-06 — — CN disclosed
CN-101254185-A Application of iridoid compound in preparing medicine for promoting nerve cell proliferation and differentiation XUANWU HOSPITAL OF CAPITAL UNI (CN) 2008-09-03 — — CN disclosed
US-20080032939-A1 Iridoid-saccharide compound and method of using same HEALTH RESEARCH, INC. (US) 2008-02-07 — — US disclosed
US-20060216251-A1 Topical formulations and methods of use TRACIE MARTYN INTERNATIONAL, LLC (US) 2006-09-28 — — US disclosed
US-20050222053-A1 Iridoid-saccharide compound and method of using same HEALTH RESEARCH, INC. (US) 2005-10-06 — — US disclosed
EP-1527783-A1 Iridoid-saccharide compound and method of using same HEALTH RESEARCH, INC. (US) 2005-05-04 — — EP disclosed
WO-1996010408-A1 CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) 1996-04-11 — — WO disclosed
US-4410710-A Conversion of iridoids to prostaglandins RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 1983-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060216251-A1 Topical formulations and methods of use CPT1B, SLC25A20, CPT1A POLB 1930/4885CTDSP1 1521/4885MEN1 2963/4885
US-20050222053-A1 Iridoid-saccharide compound and method of using same MKI67, SORD, DPYD POLB 1164/4885CTDSP1 2821/4885MEN1 3990/4885
US-20080032939-A1 Iridoid-saccharide compound and method of using same MKI67, SORD, DPYD POLB 1164/4885CTDSP1 2821/4885MEN1 3990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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