Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248053 | 1.00 | CYP1A2 (0.50) | CYP1A2GRM8GRM4TSHRAKR1C3 | |
| SCHEMBL508752 | 0.85 | AKR1C3 (0.47) | CYP1A2GRM8GRM4AKR1C3AKR1C2 | |
| SCHEMBL8962623 | 0.85 | GRM8 (0.53) | CYP1A2GRM8GRM4TSHRALDH1A1 | |
| SCHEMBL7982264 | 0.84 | CYP1A2 (0.47) | CYP1A2GRM8GRM4TSHRAKR1C3 | |
| SCHEMBL9070339 | 0.84 | TDP1 (0.51) | GRM8GRM4TSHRAKR1C3AKR1C2 | |
| SCHEMBL1640119 | 0.84 | AKR1C3 (0.55) | CYP1A2AKR1C3AKR1C2ALDH1A1TP53 | |
| SCHEMBL1640118 | 0.84 | AKR1C3 (0.55) | CYP1A2AKR1C3AKR1C2ALDH1A1TP53 | |
| SCHEMBL7982260 | 0.84 | CYP1A2 (0.47) | CYP1A2GRM8GRM4TSHRAKR1C3 | |
| SCHEMBL4658229 | 0.84 | AKR1C3 (0.46) | AKR1C3AKR1C2ALDH1A1TP53HPGD | |
| SCHEMBL10895136 | 0.83 | TDP1 (0.50) | CYP1A2GRM8GRM4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876855-A | Deoxynojirimycin And D-arabinitol Analogs And Methods Of Using | UNITED THERAPEUTICS CORP | 2015-09-02 | — | — | CN | disclosed |
| US-8975280-B2 | Deoxynojirimycin and D-arabinitol analogs and methods of using | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2015-03-10 | — | — | US | disclosed |
| EP-2023927-B1 | DEOXYNOJIRIMYCIN AND D-ARABINITOL ANALOGS AND METHODS OF USING | UNITED THERAPEUTICS CORP (US) | 2015-02-25 | — | — | EP | disclosed |
| CN-101489554-A | Deoxygirithromycin and D-arabinitol analogs and methods of use | UNITED THERAPEUTICS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2023927-A2 | DEOXYNOJIRIMYCIN AND D-ARABINITOL ANALOGS AND METHODS OF USING | United Therapeutics Corporation (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007140184-A2 | DEOXYNOJIRIMYCIN AND D-ARABINITOL ANALOGS AND METHODS OF USING | UNITED THERAPEUTICS CORPORATION (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070275998-A1 | DEOXYNOJIRIMYCIN AND D-ARABINITOL ANALOGS AND METHODS OF USING | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275998-A1 | DEOXYNOJIRIMYCIN AND D-ARABINITOL ANALOGS AND METHODS OF USING | DCXR, DERA, MAN1B1 | CYP1A2 2270/4885GRM8 3859/4885GRM4 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.