Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982260 | 1.00 | CYP1A2 (0.47) | CYP1A2TSHRKDM4EHCAR3PDK1 | |
| SCHEMBL21061692 | 0.89 | CYP1A2 (0.47) | CYP1A2TSHRKDM4EHCAR3PDK1 | |
| SCHEMBL4197252 | 0.84 | CYP1A2 (0.50) | CYP1A2TSHRKDM4EAKR1C3AKR1C2 | |
| SCHEMBL31248053 | 0.84 | CYP1A2 (0.50) | CYP1A2TSHRKDM4EAKR1C3AKR1C2 | |
| SCHEMBL1613117 | 0.81 | PDK1 (0.44) | CYP1A2TSHRKDM4EHCAR3PDK1 | |
| SCHEMBL1613121 | 0.81 | PDK1 (0.44) | CYP1A2TSHRKDM4EHCAR3PDK1 | |
| SCHEMBL1223088 | 0.80 | CYP1A2 (0.44) | CYP1A2TSHRKDM4EPDK1AKR1C2 | |
| SCHEMBL1223091 | 0.80 | CYP1A2 (0.44) | CYP1A2TSHRKDM4EPDK1AKR1C2 | |
| SCHEMBL7965821 | 0.80 | VCAM1 (0.48) | CYP1A2TSHRHCAR3PDK1AKR1C3 | |
| SCHEMBL7965816 | 0.80 | VCAM1 (0.48) | CYP1A2TSHRHCAR3PDK1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265411-B1 | ANGIOGENESIS INHIBITOR | ZENECA LIMITED (GB) | 2001-07-24 | — | — | US | disclosed |