SCHEMBL4197347

SCHEMBL4197347

CCC(O)COc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 9/20 0.68
MAPK1 P28482 3/20 0.63
LMNA P02545 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 2/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
POLB P06746 1/20 0.57
MAPT P10636 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
GAA P10253 1/20 0.55
USP2 O75604 1/20 0.54
ELANE P08246 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543110 0.90 ABCB1 (0.71) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL8926603 0.88 ABCB1 (0.69) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL2277722 0.86 ABCB1 (0.67) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL13299365 0.86 MAPK1 (0.60) ABCB1MAPK1LMNASMN1; SMN2ALDH1A1
SCHEMBL2384639 0.86 ABCB1 (0.66) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL13844833 0.86 ABCB1 (0.58) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL13096315 0.86 MAPK1 (0.61) ABCB1MAPK1LMNASMN1; SMN2HTT
SCHEMBL8414525 0.85 PLA2G4B (0.68) ABCB1MAPK1LMNAHTTALDH1A1
Water SCHEMBL8631908 0.85 ABCB1 (0.65) ABCB1MAPK1LMNASMN1; SMN2HTT
Hydrochloric Acid SCHEMBL1702139 0.85 ABCB1 (0.65) ABCB1MAPK1LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090061340-A1 HYDROXY BENZOPHENONE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
CN-111749012-B Water-based emulsion ultraviolet-resistant finishing agent and preparation method thereof 苏州浩迈纺织股份有限公司 2022-09-16 CN disclosed
CN-111749012-A Water-based emulsion ultraviolet-resistant finishing agent and preparation method thereof 苏州浩迈纺织股份有限公司 2020-10-09 CN disclosed
EP-2459519-B1 MACROPHOTOINITIATORS BASF SE (DE) 2017-11-29 EP disclosed
US-9809713-B2 Photoactivatable crosslinker compositions for surface modification INNOVATION SURFACE TECHNOLOGIES, INC. (US) 2017-11-07 US disclosed
US-9809713-B2 Photoactivatable crosslinker compositions for surface modification INNOVATION SURFACE TECHNOLOGIES, INC. (US) 2017-11-07 US disclosed
US-9116144-B2 Methods for preparing thermally responsive cell culture surfaces INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2015-08-25 US disclosed
US-9116144-B2 Methods for preparing thermally responsive cell culture surfaces INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2015-08-25 US disclosed
US-8906979-B2 Macrophotoinitiators BASF SE (DE) 2014-12-09 US disclosed
US-8709809-B2 Nanofibers containing latent reactive groups INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2014-04-29 US disclosed
US-8709809-B2 Nanofibers containing latent reactive groups INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2014-04-29 US disclosed
US-20120178844-A1 MACROPHOTOINITIATORS BASF SE (DE) 2012-07-12 US disclosed
WO-2010063612-A1 SILSESQUIOXANE PHOTOINITIATORS BASF SE (DE) 2010-06-10 WO disclosed
US-20090061340-A1 HYDROXY BENZOPHENONE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-5601756-A SUBSTITUTED BENZOPHENONE COMPOUNDS LYCUS LTD. 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178844-A1 MACROPHOTOINITIATORS CD68, CD209, MSR1 ABCB1 1821/4885MAPK1 2743/4885LMNA 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.