Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL51537 | 0.99 | ABCB1 (0.64) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| SCHEMBL2277722 | 0.98 | ABCB1 (0.67) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| Water SCHEMBL8631908 | 0.97 | ABCB1 (0.65) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9618935 | 0.88 | LMNA (0.54) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| SCHEMBL18543110 | 0.88 | ABCB1 (0.71) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9619106 | 0.87 | ABCB1 (0.61) | ABCB1MAPK1LMNA | |
| SCHEMBL10156209 | 0.86 | ABCB1 (0.62) | ABCB1MAPK1LMNA | |
| SCHEMBL4197347 | 0.85 | ABCB1 (0.68) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| SCHEMBL2384639 | 0.83 | ABCB1 (0.66) | ABCB1MAPK1LMNASMN1; SMN2HTT | |
| SCHEMBL31098144 | 0.83 | ABCB1 (0.66) | ABCB1MAPK1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416472-A1 | PHOTO-CROSS-LINKING COPOLYMERIZED HYALURONIC ACID SPONGE AND PREPARATION METHOD THEREFOR | SNVIA CO., LTD. (KR) | 2023-12-28 | — | — | US | claimed |
| WO-2022108264-A1 | PHOTO-CROSS-LINKING COPOLYMERIZED HYALURONIC ACID SPONGE AND PREPARATION METHOD THEREFOR | 주식회사 에스엔비아 | 2022-05-27 | — | — | WO | claimed |
| EP-2582745-B1 | COATING FORMULATION FOR PREPARING A HYDROPHILIC COATING | DSM IP ASSETS BV (NL) | 2019-01-09 | — | — | EP | claimed |
| US-8957125-B2 | Coating formulation for preparing a hydrophilic coating | DSM IP ASSETS B.V. (NL) | 2015-02-17 | — | — | US | claimed |
| US-20130202833-A1 | COATING FORMULATION FOR PREPARING A HYDROPHILIC COATING | DSM IP ASSETS B.V. (NL) | 2013-08-08 | — | — | US | claimed |
| EP-2582745-A1 | COATING FORMULATION FOR PREPARING A HYDROPHILIC COATING | DSM IP Assets B.V. (NL) | 2013-04-24 | — | — | EP | claimed |
| WO-2011157805-A1 | COATING FORMULATION FOR PREPARING A HYDROPHILIC COATING | DSM IP ASSETS B.V. (NL) | 2011-12-22 | — | — | WO | claimed |
| US-12270006-B2 | Coating composition, method of making a hydrophilic coating on a substrate, and medical device comprising such coating | DSM IP ASSETS B.V. (NL) | 2025-04-08 | — | — | US | disclosed |
| US-20230416472-A1 | PHOTO-CROSS-LINKING COPOLYMERIZED HYALURONIC ACID SPONGE AND PREPARATION METHOD THEREFOR | SNVIA CO., LTD. (KR) | 2023-12-28 | — | — | US | disclosed |
| US-20230183596-A1 | Coating composition, method of making a hydrophilic coating on a substrate, and medical device comprising such coating | DSM IP ASSETS B.V. (NL) | 2023-06-15 | — | — | US | disclosed |
| EP-4153645-A1 | COATING COMPOSITION, METHOD OF MAKING A HYDROPHILIC COATING ON A SUBSTRATE, AND MEDICAL DEVICE COMPRISING SUCH COATING | DSM IP Assets B.V. (NL) | 2023-03-29 | — | — | EP | disclosed |
| WO-2022108264-A1 | PHOTO-CROSS-LINKING COPOLYMERIZED HYALURONIC ACID SPONGE AND PREPARATION METHOD THEREFOR | 주식회사 에스엔비아 | 2022-05-27 | — | — | WO | disclosed |
| CN-112707673-B | Super-shrinkage type polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-6428862-B1 | PHOTOCURABLE INK CONTAINING BLACK PIGMENT, POLYMERIZABLE ACRYLIC ESTERS OF POLYOLS WITH CATIONIC AMINE OR PHOSPHONIUM GROUP, WATER, AND HIGH WATER SOLUBILITY PHOTOINITIATOR; HIGH-QUALITY IMAGE; REDUCED BLEEDING | CANON KABUSHIKI KAISHA (JP) | 2002-08-06 | — | — | US | disclosed |
| US-20020064603-A1 | Ink, ink-jet recording method using the same, and photopolymerization initiator | NOGUCHI HIROMICHI (JP) | 2002-05-30 | — | — | US | disclosed |
| US-20020061995-A1 | Acrylic ester compound and usage thereof | MITSUI CHEMICALS, INC. (JP) | 2002-05-23 | — | — | US | disclosed |
| EP-1193264-A1 | Acrylic ester compound and usage thereof | Mitsui Chemicals, Inc. (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-0953613-A2 | Ink, ink-jet recording method using the same, and photopolymerization initiator | CANON KABUSHIKI KAISHA (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0279475-B1 | BENZOPHENONE DERIVATIVES | WARD BLENKINSOP AND COMPANY LIMITED (GB) | 1992-01-15 | — | — | EP | disclosed |
| EP-0279475-A2 | Benzophenone derivatives | WARD BLENKINSOP AND COMPANY LIMITED (GB) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061995-A1 | Acrylic ester compound and usage thereof | ASS1, HAT1, EIF2B1 | ABCB1 3134/4885MAPK1 1794/4885LMNA 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.