Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479967 | 0.90 | MAPK9 (0.51) | MAPK9MAPK10ARBCL2BCL2L1 | |
| SCHEMBL3479929 | 0.89 | DRD2 (0.60) | DRD2DRD4DRD3MAPK9MAPK10 | |
| SCHEMBL6021928 | 0.83 | MAPT (0.43) | MAPK9MAPK10BCL2BCL2L1LMNA | |
| SCHEMBL7440295 | 0.82 | DRD2 (0.54) | DRD2DRD4DRD3MAPK9MAPK10 | |
| SCHEMBL7896124 | 0.82 | MAPK9 (0.52) | DRD2DRD4DRD3MAPK9MAPK10 | |
| SCHEMBL2421411 | 0.81 | MAPK9 (0.53) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2421831 | 0.81 | MAPK9 (0.55) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2428656 | 0.80 | MAPT (0.57) | DRD2DRD3MAPK9MAPK10BCL2 | |
| SCHEMBL2423054 | 0.80 | MAPK9 (0.59) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL7896125 | 0.80 | MAPK9 (0.53) | DRD2DRD4DRD3MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |