SCHEMBL419760

SCHEMBL419760

CNC(C)(C)C(C)(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14227425 0.74
SCHEMBL19135606 0.72
SCHEMBL295786 0.70
SCHEMBL2208007 0.70
SCHEMBL20629060 0.69
Hydrochloric Acid SCHEMBL28467082 0.67
Bromide SCHEMBL442644 0.67
Hydrochloric Acid SCHEMBL68105 0.67
SCHEMBL4457895 0.67
SCHEMBL8290758 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114977-A1 S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF TIAKI THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed
US-11028274-B2 Method for preventing hardener compounds to be formed from hardener precursors and extending shelf life of the dispersion WISESPRAY INTERNATIONAL LTD (FI) 2021-06-08 US disclosed
US-20200190338-A1 Method for Preventing Hardener Compounds to be Formed from Hardener Precursors and Extending Shelf Life of the Dispersion MASTON OY (FI) 2020-06-18 US disclosed
US-10023547-B2 Multifunctional primary amine, process for its preparation, and use thereof ALLNEX AUSTRIA GMBH (AT) 2018-07-17 US disclosed
US-20180110862-A1 ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE 2018-04-26 US disclosed
US-9914800-B2 Aqueous dispersions of a multifunctional primary amine, process for its preparation, and use therof ALLNEX AUSTRIA GMBH (AT) 2018-03-13 US disclosed
EP-2978313-B1 PROCESS OF MAKING PROSTACYCLIN COMPOUNDS WITH LINKER THIOL AND PEGYLATED FORMS UNITED THERAPEUTICS CORP (US) 2018-02-21 EP disclosed
US-9867883-B2 Isatoic anhydride derivatives and applications thereof THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) 2018-01-16 US disclosed
US-9744183-B2 Nucleic acid prodrugs and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2017-08-29 US disclosed
US-9695211-B2 Method for the synthesis of phosphorus atom modified nucleic acids WAVE LIFE SCIENCES JAPAN, INC. (JP) 2017-07-04 US disclosed
US-9394333-B2 Method for the synthesis of phosphorus atom modified nucleic acids WAVE LIFE SCIENCES JAPAN (JP) 2016-07-19 US disclosed
US-9376447-B2 Transfer hydrogenation of cyclopamine analogs INFINITY PHARMACEUTICALS, INC. (US) 2016-06-28 US disclosed
US-20150274881-A1 AQUEOUS DISPERSIONS OF A MULTIFUNCTIONAL PRIMARY AMINE, PROCESS FOR ITS PREPARATION, AND USE THEROF ALLNEX AUSTRIA GMBH (AT) 2015-10-01 US disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
US-20140350141-A1 MULTIFUNCTIONAL PRIMARY AMINE, PROCESS FOR ITS PREPARATION, AND USE THEREOF ALLNEX AUSTRIA GMBH (AT) 2014-11-27 US disclosed
US-20130150486-A1 CATALYST FOR URETHANE BOND FORMATION ALLNEX AUSTRIA GMBH (AT) 2013-06-13 US disclosed
US-20120316224-A1 NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF ONTORII, INC (US) 2012-12-13 US disclosed
US-20120065400-A1 Transfer Hydrogenation of Cyclopamine Analogs INFINITY PHARMACEUTICALS, INC. (US) 2012-03-15 US disclosed
US-20120065399-A1 Transfer Hydrogenation of Cyclopamine Analogs INFINITY PHARMACEUTICALS, INC. (US) 2012-03-15 US disclosed
US-20110294124-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD. (SG) 2011-12-01 US disclosed