Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969068 | 0.91 | MAPK9 (0.45) | MEN1KMT2AMAPK9MAPK10GAA | |
| SCHEMBL4970283 | 0.90 | MEN1 (0.49) | MEN1KMT2AMAPK9MAPK10GAA | |
| SCHEMBL3480450 | 0.89 | KMT2A (0.48) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL4968163 | 0.87 | KMT2A (0.51) | MEN1KMT2AMAPK9MAPK10GAA | |
| SCHEMBL4190702 | 0.87 | MEN1 (0.39) | MEN1KMT2AMAPK9MAPK10GAA | |
| SCHEMBL3479857 | 0.86 | KMT2A (0.51) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL3480005 | 0.86 | KMT2A (0.51) | MEN1KMT2AMAPK9MAPK10GAA | |
| SCHEMBL3480164 | 0.85 | KMT2A (0.51) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL3480097 | 0.85 | KMT2A (0.51) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL4968951 | 0.85 | KMT2A (0.51) | MEN1KMT2AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |