SCHEMBL4197958

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2409501	0.82	FEN1 (0.57)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL8691780	0.81	ALDH1A1 (0.58)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL7272179	0.77	FEN1 (0.58)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL3516135	0.76	FEN1 (0.46)	FEN1CYP2C19PDE4ALDHAKDM4E
	SCHEMBL11056945	0.74	CDK4 (0.51)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL13407862	0.74	FEN1 (0.49)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL17490150	0.74	FEN1 (0.48)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL9800214	0.73	FEN1 (0.45)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	SCHEMBL9767610	0.73	CA12 (0.45)	FEN1ALDH1A1TSHRCYP2C19PDE4A
	Hydrochloric Acid SCHEMBL10722765	0.73	CDK4 (0.50)	FEN1ALDH1A1TSHRCYP2C19PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.