SCHEMBL4198235

SCHEMBL4198235

CCCCCC/C=C\CCCCCCCCCCO[C@H]1[C@H](OC[C@H]2O[C@H](OCCOP(=O)(O)O)[C@H](OCCCCCCCCCCCC)[C@@H](OCCCCCCCCCCCC)[C@@H]2O)O[C@H](COC)[C@@H](OP(=O)(O)O)[C@@H]1OCC[C@@H](CCCCCCC)OC

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TLR4 O00206 9/20 0.66
▸ IGF2R P11717 4/20 0.35
▸ LPAR3 Q9UBY5 2/20 0.35
▸ LPAR1 Q92633 1/20 0.35
▸ LPAR2 Q9HBW0 1/20 0.35
▸ NR5A2 O00482 1/20 0.35
▸ NR5A1 Q13285 1/20 0.35
▸ ENPP2 Q13822 1/20 0.35
▸ TNF P01375 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197757 1.00 TLR4 (0.66) TLR4IGF2RLPAR3LPAR1LPAR2
SCHEMBL4197763 0.96 TLR4 (0.61) TLR4LPAR3LPAR1LPAR2ENPP2
SCHEMBL4191939 0.94 TLR4 (0.65) TLR4NR5A2NR5A1ENPP2
SCHEMBL4194001 0.91 TLR4 (0.67) TLR4NR5A2NR5A1TNF
SCHEMBL4191946 0.90 TLR4 (0.60) TLR4NR5A2NR5A1ENPP2
SCHEMBL4203419 0.89 TLR4 (0.57) TLR4NR5A2NR5A1TNF
SCHEMBL4197308 0.89 TLR4 (0.57) TLR4NR5A2NR5A1TNF
SCHEMBL4192270 0.85 TLR4 (0.80) TLR4
SCHEMBL4209740 0.85 TLR4 (0.69) TLR4NR5A2NR5A1ENPP2
SCHEMBL4209734 0.85 TLR4 (0.69) TLR4NR5A2NR5A1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062214-A1 Left-Side Glucose Lipid a Analogue SANKYO COMPANY, LTD. (JP) 2009-03-05 — — US claimed
EP-1702926-A1 LEVULOSE GLUCOSELIPID A ANALOGUE Sankyo Company, Limited (JP) 2006-09-20 — — EP claimed
US-20090062214-A1 Left-Side Glucose Lipid a Analogue SANKYO COMPANY, LTD. (JP) 2009-03-05 — — US disclosed
EP-1702926-A1 LEVULOSE GLUCOSELIPID A ANALOGUE Sankyo Company, Limited (JP) 2006-09-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062214-A1 Left-Side Glucose Lipid a Analogue SLC2A3, GPR119, SLC2A2 TLR4 294/4885IGF2R 488/4885LPAR3 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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