Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951181 | 0.87 | MAP3K14 (0.40) | CYP2A6MAP3K14PIK3CDGAKRPS6KA4 | |
| SCHEMBL4189449 | 0.80 | PIM1 (0.66) | PIK3CDGAKRPS6KA4STK10PIM1 | |
| SCHEMBL4189437 | 0.80 | PIM1 (0.66) | PIK3CDGAKRPS6KA4STK10PIM1 | |
| SCHEMBL4189445 | 0.80 | PIM1 (0.66) | PIK3CDGAKRPS6KA4STK10PIM1 | |
| SCHEMBL4199482 | 0.79 | RIPK2 (0.39) | CYP2A6CLK1CLK2DYRK1AALDH1A1 | |
| SCHEMBL4188009 | 0.78 | PIK3CA (0.41) | CYP2A6MAP3K14PIK3CDGAKRPS6KA4 | |
| SCHEMBL4585191 | 0.77 | SMN1; SMN2 (0.47) | CYP2A6ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29935762 | 0.77 | SMN1; SMN2 (0.47) | CYP2A6ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4192315 | 0.76 | PIK3CA (0.40) | CYP2A6MAP3K14PIK3CDGAKRPS6KA4 | |
| SCHEMBL4191687 | 0.76 | TOP2A (0.43) | MAP3K14PIK3CDGAKRPS6KA4STK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |