Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 3/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 3/20 | 0.32 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188165 | 0.80 | CISD1 (0.50) | NPC1HPGDRAB9ACLK1CLK2 | |
| SCHEMBL13951090 | 0.80 | CISD1 (0.50) | NPC1HPGDRAB9ACLK1CLK2 | |
| SCHEMBL4188161 | 0.80 | CISD1 (0.50) | NPC1HPGDRAB9ACLK1CLK2 | |
| SCHEMBL4198809 | 0.79 | CYP2A6 (0.39) | RIPK2RIPK3MEN1KMT2AKDM4E | |
| SCHEMBL4185899 | 0.79 | RIPK2 (0.38) | RIPK2RIPK3MEN1KMT2AKDM4E | |
| SCHEMBL4201167 | 0.76 | ERN1 (0.40) | RIPK2RIPK3MEN1KMT2AKDM4E | |
| SCHEMBL26315417 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL4194980 | 0.73 | ERN1 (0.38) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2882073 | 0.72 | ADORA2A (0.57) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2880423 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |