Fluoride Ion

Fluoride Ion

SCHEMBL4200159

COCn1cc[n+](C)c1.[F-]

nearest known ligand 0.48

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
PLA2G1B P04054 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
FDPS P14324 2/20 0.38
LMNA P02545 1/20 0.36
PON1 P27169 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL425211 0.98
Hydrochloric Acid SCHEMBL4211295 0.96 SMN1; SMN2 (0.44) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Iodide SCHEMBL14056822 0.96 SMN1; SMN2 (0.44) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Bromide SCHEMBL5898632 0.96 SMN1; SMN2 (0.48) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL17706400 0.80 SMN1; SMN2 (0.43) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Fluoride Ion SCHEMBL1892964 0.79 SMN1; SMN2 (0.46) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Hydrochloric Acid SCHEMBL16713822 0.79 SMN1; SMN2 (0.42) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Fluoride Ion SCHEMBL1896454 0.77 SMN1; SMN2 (0.41) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL899047 0.77 SMN1; SMN2 (0.47) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL372497 0.77 SMN1; SMN2 (0.52) SMN1; SMN2MEN1APAF1NPC1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071813-B2 Methods of using ionic liquids having a fluoride anion as solvents LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2011-12-06 US disclosed
US-20090012297-A1 Ionic liquids as solvents ENERGY, U.S. DEPARTMENT OF 2009-01-08 US disclosed