SCHEMBL42002

SCHEMBL42002

CCOC(=O)c1cc2ccccc2[nH]1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.78
HPGD P15428 4/20 0.78
ALDH1A1 P00352 4/20 0.78
RAB9A P51151 3/20 0.78
LMNA P02545 3/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
NPC1 O15118 2/20 0.78
MAPT P10636 2/20 0.78
GAA P10253 2/20 0.78
MEN1 O00255 1/20 0.78
GLA P06280 1/20 0.78
KMT2A Q03164 1/20 0.78
ATM Q13315 1/20 0.78
HSD17B10 Q99714 2/20 0.70
ALOX15 P16050 1/20 0.67
L3MBTL1 Q9Y468 2/20 0.65
HTT P42858 1/20 0.65
HRH3 Q9Y5N1 1/20 0.65
MMP13 P45452 5/20 0.63
MMP2 P08253 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580772 1.00 KDM4E (0.78) KDM4EHPGDALDH1A1RAB9ALMNA
Hydrochloric Acid SCHEMBL9036642 0.98 KDM4E (0.76) KDM4EHPGDALDH1A1RAB9ALMNA
Hydrochloric Acid SCHEMBL16115604 0.98 KDM4E (0.76) KDM4EHPGDALDH1A1RAB9ALMNA
Indole-2-Carboxylic Acid SCHEMBL14158279 0.94 KDM4E (0.70) KDM4EHPGDALDH1A1RAB9ALMNA
Indole SCHEMBL29130809 0.90 KDM4E (0.65) KDM4EHPGDALDH1A1RAB9ALMNA
SCHEMBL5567460 0.88 KDM4E (1.00) KDM4EHPGDALDH1A1RAB9ALMNA
SCHEMBL7169528 0.88 KDM4E (0.61) KDM4EHPGDALDH1A1RAB9ALMNA
Hydrochloric Acid SCHEMBL29291163 0.87 KDM4E (0.60) KDM4EHPGDALDH1A1RAB9ALMNA
SCHEMBL5289613 0.85 DRD2 (0.59) KDM4EHPGDALDH1A1RAB9ALMNA
SCHEMBL4557755 0.84 KDM4E (0.59) KDM4EHPGDALDH1A1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 CN claimed
CN-119613320-A Synthesis method of compound 3-iodo-1H-indole-2-carboxylic acid 上海毕臣生化科技有限公司 2025-03-14 CN claimed
CN-119350315-A 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof 南开大学 2025-01-24 CN claimed
CN-115843271-B Indole derivatives and their use for the treatment of cancer 克洛德贝纳尔-里昂第一大学 2024-08-13 CN claimed
CN-117603188-A Indole and quinoline skeleton-containing compound and application thereof 苏州卫生职业技术学院 2024-02-27 CN claimed
CN-117362291-A Tetrahydro-beta-carboline phenol derivative, preparation method and application thereof, and whitening cream 广州番禺职业技术学院 2024-01-09 CN claimed
CN-114591295-B Pyridine salt-containing N- (indolyl) -N' - (substituted) propyl hydrazide derivative, preparation method and application thereof 贵州大学 2023-11-07 CN claimed
CN-113831275-B Indole-substituted 6-phenylindenoindole derivative and preparation method and application thereof 上海兆维科技发展有限公司 2023-03-28 CN claimed
CN-114605303-A Synthesis method of delavirdine and intermediate thereof 武汉工程大学 2022-06-10 CN claimed
CN-114591295-A Pyridine salt-containing N- (indoleacyl) -N' - (substituted) propyl hydrazide derivative, and preparation method and application thereof 贵州大学 2022-06-07 CN claimed
WO-2001016097-A1 PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS SUGEN, INC. (US) 2001-03-08 WO claimed
CN-1144529-A Heterocyclic compounds, their preparation and use NOVO NORDISK AS (DK) 1997-03-05 CN claimed
JP-H08506348-A 1996-07-09 JP claimed
EP-0703911-A1 SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS PFIZER (US) 1996-04-03 EP claimed
WO-1994029290-A1 SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS PFIZER INC. (US) 1994-12-22 WO claimed
EP-0605595-A1 FINE DISPERSION OF MELANIC PIGMENTS, ITS PREPARATION AND UTILISATION IN COSMETICS. OREAL (FR) 1994-07-13 EP claimed
CN-1088209-A Heterogeneous ring compound WELLCOME FOUND (GB) 1994-06-22 CN claimed
EP-0575603-A1 PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS. OREAL (FR) 1993-12-29 EP claimed
WO-1993013743-A1 PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS L'OREAL (FR) 1993-07-22 WO claimed
WO-1993005754-A1 FINE DISPERSION OF MELANIC PIGMENTS, ITS PREPARATION AND UTILISATION IN COSMETICS L'OREAL (FR) 1993-04-01 WO claimed