Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.69 |
| ▸ | PGR | P06401 | 9/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.69 |
| ▸ | AR | P10275 | 6/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196455 | 0.89 | NR3C1 (0.69) | NR3C1PGRNR3C2AR | |
| SCHEMBL13747323 | 0.85 | NR3C1 (0.83) | NR3C1PGRNR3C2AR | |
| SCHEMBL4197858 | 0.83 | NR3C1 (0.79) | NR3C1PGRNR3C2AR | |
| SCHEMBL4197861 | 0.83 | NR3C1 (0.79) | NR3C1PGRNR3C2AR | |
| SCHEMBL4198017 | 0.82 | NR3C1 (0.53) | NR3C1PGRNR3C2AR | |
| SCHEMBL13747596 | 0.82 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL4186486 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4188773 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4186483 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4192863 | 0.80 | NR3C1 (0.71) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |