Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 6/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323279 | 0.93 | CNR2 (0.44) | CNR2CNR1L3MBTL1TYK2KDM5A | |
| SCHEMBL13929017 | 0.86 | PDE4B (0.50) | CNR2CNR1ALDH1A1PDE4B | |
| SCHEMBL13929020 | 0.85 | KDM5A (0.43) | CNR2TYK2KDM5AALDH1A1PDE4B | |
| SCHEMBL4184529 | 0.85 | KDM5A (0.43) | CNR2TYK2KDM5AALDH1A1PDE4B | |
| SCHEMBL13929028 | 0.80 | L3MBTL1 (0.53) | CNR2CNR1L3MBTL1ALDH1A1 | |
| SCHEMBL4200607 | 0.80 | L3MBTL1 (0.53) | CNR2CNR1L3MBTL1ALDH1A1 | |
| SCHEMBL4191409 | 0.80 | PDE4B (0.50) | CNR2CNR1PDE4B | |
| SCHEMBL4185131 | 0.79 | PDE4B (0.41) | CNR2CNR1TYK2ALDH1A1PDE4B | |
| SCHEMBL8299116 | 0.78 | CNR2 (0.48) | CNR2CNR1L3MBTL1TYK2ALDH1A1 | |
| SCHEMBL4189964 | 0.78 | KDM5A (0.41) | CNR2CNR1TYK2KDM5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090035313-A1 | Compounds | PFIZER INC. | 2009-02-05 | — | — | US | claimed |
| US-20050020611-A1 | Compounds | PFIZER INC. | 2005-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020611-A1 | Compounds | NQO1, NAMPT, NNT | CNR2 571/4885CNR1 529/4885L3MBTL1 4529/4885 |
| US-20090035313-A1 | Compounds | NQO1, NAMPT, NNT | CNR2 571/4885CNR1 529/4885L3MBTL1 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.