Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | MEN1 | O00255 | 6/20 | 0.77 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.77 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204948 | 0.91 | KMT2A (0.77) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4211504 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4216370 | 0.84 | MAPT (0.79) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4206875 | 0.82 | KMT2A (0.83) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL13802443 | 0.81 | MAPT (0.74) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4209133 | 0.81 | MAPT (0.78) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4217682 | 0.81 | MAPT (0.77) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4211567 | 0.80 | MAPT (0.71) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL6480116 | 0.79 | CTSV (0.58) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4212246 | 0.77 | MAPT (1.00) | KMT2AMAPTMEN1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | KMT2A 2408/4885MAPT 6/4885MEN1 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.