Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4200786 | 1.00 | TSHR (0.42) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4200784 | 0.94 | SMN1; SMN2 (0.49) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4200789 | 0.94 | SMN1; SMN2 (0.49) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14493389 | 0.86 | ALDH1A1 (0.53) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7755420 | 0.86 | ALDH1A1 (0.53) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL990584 | 0.80 | ALDH1A1 (0.63) | TSHRPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5070821 | 0.79 | ALDH1A1 (0.47) | TSHRPOLBALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5068756 | 0.79 | ALDH1A1 (0.47) | TSHRPOLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL472107 | 0.78 | TSHR (0.59) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3780920 | 0.78 | TSHR (0.46) | TSHRPOLBMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511110-B2 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| US-7385000-B2 | Silicone rubber composition having improved storage stability | WACKER CHEMIE AG (DE) | 2008-06-10 | — | — | US | disclosed |
| US-20060135689-A1 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE GMBH (DE) | 2006-06-22 | — | — | US | disclosed |
| US-20060084745-A1 | Silicone rubber composition having improved storage stability | WACKER-CHEMIE GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
| US-6359098-B1 | SHELF LIFE AS ONE-COMPONENT ADDITION-CURABLE ORGANOPOLYSILOXANES, AND EXTENDED POT LIFE FOR TWO-COMPONENT ADDITION-CURABLE ORGANOPOLYSILOXANES, WITHOUT COMPROMISING CROSSLINKING RATES OR LEVELS | WACKER-CHEMIE GMBH (DE) | 2002-03-19 | — | — | US | disclosed |
| US-6252028-B1 | PLATINUM CATALYST | WACKER-CHEMIE GMBH (DE) | 2001-06-26 | — | — | US | disclosed |