SCHEMBL4201262

SCHEMBL4201262

C=COC(=O)CC(CCCC)=C(C=CC(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.37
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
ACHE P22303 1/20 0.32
BACE1 P56817 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8901060 0.87 HCAR2 (0.33) HCAR2
SCHEMBL6906062 0.79 HCAR2 (0.36) HCAR2POLBPOLA1ACHEBACE1
Fumaric Acid SCHEMBL9507155 0.75 TSHR (0.57) HCAR2TSHRALDH1A1LMNA
Fumaric Acid SCHEMBL9507151 0.75 TSHR (0.57) HCAR2TSHRALDH1A1LMNA
SCHEMBL28187703 0.73 TSHR (0.44) TSHRPOLBPOLA1ALDH1A1LMNA
SCHEMBL277785 0.72 HCAR2 (0.45) HCAR2TSHRALDH1A1
SCHEMBL93600 0.72
Maleic Acid SCHEMBL11159534 0.72 TSHR (0.53) HCAR2TSHRPOLBPOLA1ALDH1A1
Ethylene SCHEMBL624958 0.70 TSHR (0.53) TSHRALDH1A1LMNA
SCHEMBL5922618 0.69 TSHR (0.52) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753355-B2 Latex crosslinking with blocked nitrile oxides or epoxy silanes DOW GLOBAL TECHNOLOGIES INC. 2004-06-22 US claimed
US-20030229153-A1 Latex crosslinking with blocked nitrile oxides or epoxy silanes TRINSEO EUROPE GMBH (CH) 2003-12-11 US claimed
JP-2003517511-A 2003-05-27 JP claimed
EP-1244747-A1 STORAGE STABLE, FOAMABLE, SINGLE LATEX/EPOXY EMULSION DOW GLOBAL TECHNOLOGIES INC. (US) 2002-10-02 EP claimed
WO-2001042358-A1 STORAGE STABLE, FOAMABLE, SINGLE LATEX/EPOXY EMULSION DOW GLOBAL TECHNOLOGIES INC. (US) 2001-06-14 WO claimed
US-4567099-A CONJUGATED DIENE-ALKENYL AROMATIC COPOLYMERS, PARTICLE SIZES THE DOW CHEMICAL COMPANY (US) 1986-01-28 US claimed
EP-1354009-B1 BIMODAL AQUEOUS POLYMER DISPERSIONS DOW GLOBAL TECHNOLOGIES INC (US) 2009-03-04 EP disclosed
US-6753355-B2 Latex crosslinking with blocked nitrile oxides or epoxy silanes DOW GLOBAL TECHNOLOGIES INC. 2004-06-22 US disclosed
US-20030229153-A1 Latex crosslinking with blocked nitrile oxides or epoxy silanes TRINSEO EUROPE GMBH (CH) 2003-12-11 US disclosed
EP-1354009-A1 BIMODAL AQUEOUS POLYMER DISPERSIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-10-22 EP disclosed
WO-2002070615-A1 BIMODAL AQUEOUS POLYMER DISPERSIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-12 WO disclosed
US-4567099-A CONJUGATED DIENE-ALKENYL AROMATIC COPOLYMERS, PARTICLE SIZES THE DOW CHEMICAL COMPANY (US) 1986-01-28 US disclosed