Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.42 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222100 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL15963882 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL300405 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL1310354 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL7870044 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL15961754 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL513822 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL15961758 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL15963878 | 1.00 | MAOB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT | |
| SCHEMBL9733602 | 0.96 | THRB (0.44) | MAOBL3MBTL1MAPK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9211250-B2 | Heterogeneous polymeric micelles for intracellular delivery | UNIVERSITY OF WASHINGTON (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140235790-A1 | CARBOHYDRATE-BASED COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2014-08-21 | — | — | US | disclosed |
| US-20120021514-A1 | HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY | PHASERX, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2331069-A1 | HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY | University Of Washington (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010021770-A1 | HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY | UNIVERSITY OF WASHINGTON (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235790-A1 | CARBOHYDRATE-BASED COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY | CD44, CSGALNACT1, KRTCAP2 | MAOB 4192/4885L3MBTL1 4743/4885MAPK1 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.