⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23185124 | 0.83 | LMNA (0.38) | — | |
| SCHEMBL15945376 | 0.79 | KMT2A (0.48) | — | |
| SCHEMBL12092123 | 0.78 | — | — | |
| SCHEMBL23940295 | 0.78 | — | — | |
| SCHEMBL19415970 | 0.74 | — | — | |
| SCHEMBL20852576 | 0.74 | — | — | |
| SCHEMBL7594795 | 0.74 | — | — | |
| SCHEMBL8703324 | 0.74 | — | — | |
| SCHEMBL18324419 | 0.74 | — | — | |
| SCHEMBL11264137 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102194-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS JNK MODULATORS | F. Hoffmann-Roche AG (CH) | 2009-09-23 | — | — | EP | claimed |
| WO-2008068171-A9 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS JNK MODULATORS | HOFFMANN LA ROCHE (CH) | 2009-07-16 | — | — | WO | claimed |
| WO-2008068171-A1 | SUBSTITUTED PYRIMIDINES AND THEIR USE AS JNK MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-12 | — | — | WO | claimed |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| WO-2023180485-A1 | ANTIBODY-CONJUGATES FOR TARGETING OF TUMOURS EXPRESSING TROP-2 | SYNAFFIX B.V. (NL) | 2023-09-28 | — | — | WO | disclosed |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-20230270876-A1 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | NOVARTIS AG (CH) | 2023-08-31 | — | — | US | disclosed |
| EP-3188764-B1 | POLYMER AND CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING INCLUDING THE POLYMER | CANON KK (JP) | 2023-08-23 | — | — | EP | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230242586-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2008-12-25 | — | — | US | disclosed |
| US-20080274052-A1 | RADIOFLORINATION METHODS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | US | disclosed |
| US-7439309-B2 | Silver halide photographic light-sensitive material, photographic emulsion, and mercapto group-containing polymer compound used for them | FUJIFILM CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20080164211-A1 | Mixed-Modal Anion-Exchanged Type Separation Material | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| WO-2008079924-A1 | IMMUNE RESPONSE MODIFIER COMPOSITIONS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
| WO-2007100634-A2 | IMMUNE RESPONSE MODIFIER CONJUGATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-07 | — | — | WO | disclosed |
| US-7172905-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2007-02-06 | — | — | US | disclosed |
| US-4313949-A | Method of producing an inhibitory effect on blood platelet aggregation | A. H. ROBINS COMPANY, INC. (US) | 1982-02-02 | — | — | US | disclosed |