Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 17/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746749 | 0.87 | SCARB1 (0.63) | SCARB1CYP3A4PTGDR2 | |
| SCHEMBL4195483 | 0.85 | SCARB1 (0.64) | SCARB1CYP3A4PTGDR2 | |
| SCHEMBL13746614 | 0.83 | SCARB1 (0.59) | SCARB1CYP3A4PTGDR2 | |
| SCHEMBL4202035 | 0.83 | SCARB1 (0.66) | SCARB1CYP3A4PTGDR2 | |
| SCHEMBL4211410 | 0.83 | SCARB1 (0.55) | SCARB1 | |
| SCHEMBL13747451 | 0.81 | SCARB1 (0.56) | SCARB1PTGDR2 | |
| SCHEMBL4193417 | 0.79 | SCARB1 (0.46) | SCARB1 | |
| SCHEMBL4026317 | 0.79 | SCARB1 (0.46) | SCARB1 | |
| SCHEMBL4200388 | 0.77 | SCARB1 (0.73) | SCARB1 | |
| SCHEMBL4205587 | 0.75 | SCARB1 (0.73) | SCARB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |