⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14537520 | 0.82 | — | — | |
| SCHEMBL679862 | 0.78 | NLRP3 (0.39) | — | |
| SCHEMBL12456989 | 0.78 | NLRP3 (0.39) | — | |
| SCHEMBL7112088 | 0.77 | — | — | |
| SCHEMBL5784859 | 0.73 | — | — | |
| SCHEMBL12854170 | 0.73 | — | — | |
| SCHEMBL3511747 | 0.73 | — | — | |
| SCHEMBL10771596 | 0.73 | — | — | |
| SCHEMBL84504 | 0.73 | — | — | |
| SCHEMBL597046 | 0.71 | NLRP3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322996-A1 | POLYMER-INTERACTION MOLECULE CONJUGATES AND METHODS OF USE | LIFE TECHNOLOGIES AS (NO) | 2023-10-12 | — | — | US | disclosed |
| US-11673100-B2 | Systems and methods for integrated solar photodialysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-13 | — | — | US | disclosed |
| EP-3154997-B9 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3753578-A1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | Novartis AG (CH) | 2020-12-23 | — | — | EP | disclosed |
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| US-10449739-B2 | Hydrogel contact lenses with lubricious coating thereon | NOVARTIS AG (CH) | 2019-10-22 | — | — | US | disclosed |
| EP-3082877-B1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2019-08-28 | — | — | EP | disclosed |
| US-10016510-B2 | Immunogenic composition in emulsion form | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2018-07-10 | — | — | US | disclosed |
| US-9968673-B2 | Immunogenic composition in emulsion form comprising two dispersed phases, one comprising an antigen and the other comprising an immunostimulating agent | Commissariat á l'ènergie atomique et aux ènergies alternatives (FR) | 2018-05-15 | — | — | US | disclosed |
| US-20180079158-A1 | HYDROGEL CONTACT LENSES WITH LUBRICIOUS COATING THEREON | ALCON INC. (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20100069571-A1 | Thioester-Terminated Water Soluble Polymers and Method of Modifying the N-Terminus of a Polypeptide Therewith | NEKTAR THERAPEUTICS (US) | 2010-03-18 | — | — | US | disclosed |
| US-7511095-B2 | Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |
| US-20090035215-A1 | RADIOFLUORINATION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-02-05 | — | — | US | disclosed |
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2008-12-25 | — | — | US | disclosed |
| US-20080166362-A1 | New effector conjugates, process for their production and their pharmaceutical use | BERGER MARKUS | 2008-07-10 | — | — | US | disclosed |
| US-20080166362-A1 | New effector conjugates, process for their production and their pharmaceutical use | BERGER MARKUS | 2008-07-10 | — | — | US | disclosed |
| US-7335775-B2 | Effector conjugates, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2008-02-26 | — | — | US | disclosed |
| US-7335775-B2 | Effector conjugates, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2008-02-26 | — | — | US | disclosed |
| US-20070088060-A1 | New effector conjugates, process for their production and their pharmaceutical use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-04-19 | — | — | US | disclosed |
| US-20070088060-A1 | New effector conjugates, process for their production and their pharmaceutical use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-04-19 | — | — | US | disclosed |