Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 7/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5402661 | 0.79 | OPRM1 (0.62) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL1551563 | 0.79 | OPRM1 (0.55) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL28093355 | 0.78 | OPRM1 (0.50) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL14661931 | 0.76 | OPRM1 (0.51) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL27377417 | 0.76 | OPRM1 (0.51) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL14661822 | 0.75 | OPRM1 (0.47) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL27377408 | 0.74 | OPRM1 (0.49) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL22488577 | 0.73 | OPRM1 (0.61) | OPRM1OPRL1DPP4CARM1PRMT6 | |
| SCHEMBL5321273 | 0.73 | CARM1 (0.40) | CARM1PRMT6SIGMAR1 | |
| SCHEMBL1551250 | 0.73 | OPRM1 (0.61) | OPRM1OPRL1DPP4CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022045-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | VENKATRAMAN SHANKAR (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022045-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | CCND3, CDK3, CDK2 | OPRM1 2843/4885OPRL1 3900/4885DPP4 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.