Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419537 | 0.83 | ALOX15 (0.39) | BLMALOX15PMP22KMT2ATRPV1 | |
| SCHEMBL420604 | 0.80 | TSHR (0.41) | BLMALOX15KMT2ATRPV1TSHR | |
| SCHEMBL421702 | 0.78 | TRPV1 (0.41) | BLMALOX15TRPV1TSHRTDP1 | |
| SCHEMBL422004 | 0.78 | TRPV1 (0.38) | TRPV1TSHRTDP1CHRM2CHRM4 | |
| SCHEMBL420644 | 0.77 | TRPV1 (0.47) | BLMTRPV1TSHRDPP4DPP8 | |
| SCHEMBL421635 | 0.76 | TRPV1 (0.39) | BLMTRPV1TSHRTDP1CHRM2 | |
| SCHEMBL420341 | 0.76 | TRPV1 (0.50) | TRPV1TSHRTDP1CHRM2CHRM4 | |
| SCHEMBL421642 | 0.75 | TSHR (0.44) | BLMALOX15TRPV1TSHRTDP1 | |
| SCHEMBL420619 | 0.75 | TSHR (0.44) | BLMTRPV1TSHRTDP1CHRM2 | |
| SCHEMBL14396088 | 0.74 | TRPV1 (0.53) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | BLM 1580/4885ALOX15 4521/4885PMP22 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.