Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442113 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| SCHEMBL10975327 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| SCHEMBL11550922 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL41048 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL8495527 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| SCHEMBL73078 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL16698377 | 0.95 | HRH3 (0.59) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL737731 | 0.94 | HRH3 (0.57) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| SCHEMBL16335517 | 0.92 | HRH3 (0.55) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE | |
| SCHEMBL2747040 | 0.92 | HRH3 (0.70) | HRH3CYP1A2MAPK1SMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| US-20230257486-A1 | PROCESS FOR OBTAINING GLYCAN EXTRACTS FROM APPLE POMACE, PROCESS FOR PRODUCING FUNCTIONALIZED GLYCANS, AND FUNCTIONALIZED GLYCAN THAT CAN BE PRODUCED BY THE PROCESS AND ITS USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-08-17 | — | — | US | claimed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | claimed |
| EP-4182360-A1 | PROCESS FOR OBTAINING GLYCAN EXTRACTS FROM APPLE POMACE, PROCESS FOR PRODUCING FUNCTIONALIZED GLYCANS, AND FUNCTIONALIZED GLYCAN THAT CAN BE PRODUCED BY THE PROCESS AND ITS USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-05-24 | — | — | EP | claimed |
| CN-110551079-B | Preparation method of high-purity difenidol hydrochloride | 株洲千金药业股份有限公司 | 2021-04-06 | — | — | CN | claimed |
| CN-110627744-A | Preparation method of difenidol hydrochloride intermediate | 株洲千金药业股份有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110551079-A | Preparation method of high-purity difenidol hydrochloride | ZHUZHOU QIANJIN PHARMACEUTICAL CO LTD | 2019-12-10 | — | — | CN | claimed |
| CN-106749101-B | A kind of preparation method of difenidol hydrochloride | 湖南千金湘江药业股份有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-104402799-B | A kind of N-(3-chloropropyl) piperidines process for purification | 河南慧锦药业有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-106008396-A | Impurity in difenidol hydrochloride intermediate N-(3-chloropropyl) piperidine and preparation method of impurity | 河南豫辰药业股份有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-106018598-A | Method for measuring content of byproducts in difenidol hydrochloride intermediate N-(3-chloropropyl) piperidine | 河南豫辰药业股份有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-104402799-A | N-(3-methyl chlorine) piperidine refining method | HENAN HUIJIN PHARMACEUTICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | claimed |
| US-6384031-B1 | — | — | None | — | — | US | disclosed |
| JP-1261382-A | — | — | None | — | — | JP | disclosed |
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | ZHEJIANG UNIVERSITY (CN) | 2025-09-02 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |
| US-3935191-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3932456-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | PIK3R5, PIK3CA, PIK3R1 | HRH3 3040/4885CYP1A2 1155/4885MAPK1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.