⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42034 | 0.97 | HRH3 (0.65) | — | |
| SCHEMBL10975327 | 0.97 | HRH3 (0.65) | — | |
| Hydrochloric Acid SCHEMBL737731 | 0.97 | HRH3 (0.57) | — | |
| SCHEMBL6442113 | 0.97 | HRH3 (0.65) | — | |
| SCHEMBL11550922 | 0.95 | HRH3 (0.62) | — | |
| SCHEMBL16335517 | 0.95 | HRH3 (0.55) | — | |
| Hydrochloric Acid SCHEMBL8495527 | 0.95 | HRH3 (0.62) | — | |
| Hydrochloric Acid SCHEMBL41048 | 0.95 | HRH3 (0.62) | — | |
| Hydrochloric Acid SCHEMBL16698377 | 0.92 | HRH3 (0.59) | — | |
| SCHEMBL6442647 | 0.92 | HRH3 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | claimed |
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| EP-4392411-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | Hovione Farmaciencia SA (PT) | 2024-07-03 | — | — | EP | claimed |
| CN-118159526-A | Process for preparing chloroalkyl substituted cyclic amines | 好利安药理股份公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | claimed |
| WO-2023030667-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE SCIENTIA (IE) | 2023-03-09 | — | — | WO | claimed |
| EP-3433249-B1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL SCIENT IND RES (IN) | 2022-11-09 | — | — | EP | claimed |
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | claimed |
| EP-3707140-B1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS | COUNCIL SCIENT IND RES (IN) | 2021-10-13 | — | — | EP | claimed |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-11-05 | — | — | US | claimed |
| EP-3707140-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | Council of Scientific and Industrial Research (IN) | 2020-09-16 | — | — | EP | claimed |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-26 | — | — | US | claimed |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-03-28 | — | — | US | claimed |
| EP-3433249-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | Council Of Scientific & Industrial Research (IN) | 2019-01-30 | — | — | EP | claimed |
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | claimed |
| US-7851623-B2 | Chemical process | ASTRAZENECA AB (SE) | 2010-12-14 | — | — | US | claimed |
| US-5852189-A | Tertiaryaminoalkyllithium initiators and the preparation thereof | BRIDGESTONE CORPORATION (JP) | 1998-12-22 | — | — | US | claimed |
| EP-0850942-A1 | Tertiaryaminoalkyllithium initiators and the preparation thereof | Bridgestone Corporation (JP) | 1998-07-01 | — | — | EP | claimed |
| EP-4630424-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | Third Harmonic Bio, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |