Cyclopropane

Cyclopropane

SCHEMBL420362

C1CC1.C=C(C)C(=O)OCCOC(=O)C(=C)C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.65
TSHR P16473 5/20 0.57
ALDH1A1 P00352 5/20 0.50
TDP1 Q9NUW8 3/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
EPHX1 P07099 1/20 0.38
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
LMNA P02545 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL117214 1.00 THRB (0.65) THRBTSHRALDH1A1TDP1POLB
Cyclopentane SCHEMBL2397167 1.00 THRB (0.65) THRBTSHRALDH1A1TDP1POLB
SCHEMBL60085 1.00 THRB (0.65) THRBTSHRALDH1A1TDP1POLB
SCHEMBL15636 0.92 THRB (0.74) THRBTSHRALDH1A1TDP1POLB
SCHEMBL6142874 0.92 THRB (0.74) THRBTSHRALDH1A1TDP1POLB
SCHEMBL11418632 0.91 THRB (0.57) THRBTSHRALDH1A1TDP1POLB
Ethylene SCHEMBL632736 0.90 THRB (0.71) THRBTSHRALDH1A1TDP1POLB
Ethylene SCHEMBL2367613 0.90 THRB (0.71) THRBTSHRALDH1A1TDP1POLB
Ethylene SCHEMBL619217 0.90 THRB (0.71) THRBTSHRALDH1A1TDP1POLB
Ethylene SCHEMBL955493 0.90 THRB (0.71) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111163922-B Natural rubber mould-free manufacturing method 国家科学技术发展局 2023-03-14 CN claimed
US-20200269493-A1 A METHOD FOR MOLD-FREE MANUFACTURING OF NATURAL RUBBER ARTICLES NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY (TH) 2020-08-27 US claimed
US-10162082-B2 Ophthalmic lens material and ophthalmic lens of such material MIICS & PARTNERS (SHENZHEN) CO., LTD. (CN) 2018-12-25 US claimed
US-20180210114-A1 OPHTHALMIC LENS MATERIAL AND OPHTHALMIC LENS OF SUCH MATERIAL MIICS & PARTNERS (SHENZHEN) CO., LTD. (CN) 2018-07-26 US claimed
EP-1190866-B1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK CO (US) 2004-03-03 EP claimed
EP-1190866-A1 Photocrosslinkable latex protective overcoat for imaging elements EASTMAN KODAK COMPANY (US) 2002-03-27 EP claimed
US-6352805-B1 IMAGED ELEMENT HAVING PROTECTIVE OVERCOAT OF COMPOSITION COMPRISING REACTION PRODUCT OF WATER-DISPERSIBLE LATEX PARTICLES AND COPOLYMERIZABLE MULTIFUNCTIONAL MONOMER CROSSLINKED WITH ULTRAVIOLET LIGHT IN PRESENCE OF INITIATOR EASTMAN KODAK COMPANY 2002-03-05 US claimed
US-20010056133-A1 Curable compositions with antimicrobial properties MONTGOMERY R ERIC (US) 2001-12-27 US claimed
EP-1056430-A2 CURABLE COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES Oraceutical, LLC (US) 2000-12-06 EP claimed
WO-1999042080-A2 CURABLE COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES ORACEUTICAL, LLC (US) 1999-08-26 WO claimed
US-4430418-A AROMATIC POLYCARBOXYLIC COMPOUND, AND POLYFUNCTIONAL ACRYLATE COMPOUND WITH PROMOTER AND BIIMIDAZOLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-07 US claimed
US-4416973-A Radiation-sensitive polyimide precursor composition derived from a diaryl fluoro compound E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US claimed
US-4414312-A Photopolymerizable polyamide ester resin compositions containing an oxygen scavenger E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-08 US claimed
US-4410612-A POLYIMIDE FROM CURED UNSATURED ESTER OF POLYAMIDEACID POLYFUNCTIONAL ACRYLATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-18 US claimed
EP-0084269-A2 Radiation-sensitive polyimide precursor composition derived from a diaryl fluoro compound E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP claimed
US-4369247-A Process of producing relief structures using polyamide ester resins E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US claimed
US-4329419-A POLYAMIDEESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-11 US claimed
EP-0047184-A2 Radiation polymerizable composition for forming heat-resistant relief structures on electrical devices such as semiconductors and capacitors E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-10 EP claimed
US-4146592-A BLEND OF CROSSLINKED AND UNCROSSLINKED DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-03-27 US claimed
US-3933754-A CROSSLINKED WITH DIMETHACRYLATES, DIVINYLBENZENE OR DIALLYL PHTHALATE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US claimed