SCHEMBL4204455

SCHEMBL4204455

NCC(=O)OC(=O)/C=C/C(=O)OC(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
GLRA1 P23415 1/20 0.33
SLC6A9 P48067 1/20 0.33
OR51E2 Q9H255 1/20 0.33
ATM Q13315 1/20 0.31
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
LMNA P02545 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
TSHR P16473 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL558297 1.00 HCAR2 (0.35) HCAR2KEAP1NFE2L2GLRA1SLC6A9
SCHEMBL558370 0.91
SCHEMBL10602462 0.91 HCAR2 (0.45) HCAR2GLRA1SLC6A9OR51E2GABRR1
SCHEMBL10602450 0.91 HCAR2 (0.45) HCAR2GLRA1SLC6A9OR51E2GABRR1
SCHEMBL28548482 0.85 GSTP1 (0.31) LMNAKDM4E
SCHEMBL4587745 0.79
SCHEMBL288431 0.78
Potassium SCHEMBL31261840 0.77 TSHR (0.38) TSHR
SCHEMBL6753492 0.76 GLRA1 (0.41) GLRA1SLC6A9OR51E2GABRR1LMNA
SCHEMBL6258848 0.76 GLRA1 (0.41) GLRA1SLC6A9OR51E2GABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3263117-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD. (AU) 2018-01-03 EP claimed
EP-3216445-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD. (AU) 2017-09-13 EP claimed
US-9757455-B2 Oral therapeutic compound delivery system JOHNSON & JOHNSON CONSUMER INC. (US) 2017-09-12 US claimed
CN-106581755-A Antibacterial fibroin-based bionic coating and preparation method thereof 苏州纳贝通环境科技有限公司 2017-04-26 CN claimed
CN-106540316-A A kind of antibacterial liquid medical dressing and preparation method thereof 苏州艾博迈尔新材料有限公司 2017-03-29 CN claimed
EP-1750677-B1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD (AU) 2017-02-01 EP claimed
CN-106279575-A A kind of temperature sensitive type composite aquogel and preparation method thereof 林春梅 2017-01-04 CN claimed
CN-106237374-A A kind of medical antibacterial aerogel dressing and preparation method thereof 林春梅 2016-12-21 CN claimed
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
US-20130065885-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD. (AU) 2013-03-14 US claimed
US-20090311327-A1 Oral Therapeutic Compound Delivery System IMAGINOT PTY LTD (AU) 2009-12-17 US claimed
US-20080287456-A1 Oral Therapeutic Compound Delivery System IMAGINOT PTY LTD (AU) 2008-11-20 US claimed
EP-1954298-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM Imaginot Pty Ltd. (AU) 2008-08-13 EP claimed
WO-2007059591-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD (AU) 2007-05-31 WO claimed
EP-1750677-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM Imaginot Pty Ltd. (AU) 2007-02-14 EP claimed
WO-2005115345-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD (AU) 2005-12-08 WO claimed
CN-109054648-A Serosity combination for chemically mechanical polishing LTCAM有限公司 2018-12-21 CN disclosed
US-20050276847-A1 Oral delivery system IMAGINOT PTY LTD. (AU) 2005-12-15 US disclosed
WO-2005115345-A1 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM IMAGINOT PTY LTD (AU) 2005-12-08 WO disclosed