SCHEMBL28548482

SCHEMBL28548482

C/C=C/C(=O)OC(=O)CN

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204455 0.85 HCAR2 (0.35) KDM4ELMNA
SCHEMBL558297 0.85 HCAR2 (0.35) KDM4ELMNA
SCHEMBL988310 0.81 ALDH1A1 (0.35) GSTP1
SCHEMBL2261535 0.81 ALDH1A1 (0.35) GSTP1
SCHEMBL1238290 0.81 ALDH1A1 (0.35) GSTP1
SCHEMBL3987676 0.80 MGAM (0.46) GSTP1
SCHEMBL29229911 0.79 GSTP1 (0.32) GSTP1
SCHEMBL29036628 0.77 TSHR (0.42) GSTP1
SCHEMBL10602450 0.77 HCAR2 (0.45) KDM4ELMNA
SCHEMBL558370 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112585116-A Synthesis of (2S, 3R, 4R) -4, 5-dihydroxyisoleucine and derivatives thereof 海德堡医药研究有限责任公司 2021-03-30 CN disclosed