SCHEMBL420467

SCHEMBL420467

CCCCCCC(Cl)CCl

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
SLC22A1 O15245 1/20 0.39
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412105 1.00 TSHR (0.46) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL19462782 1.00 TSHR (0.46) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL4896810 1.00 TSHR (0.46) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL2369634 1.00 TSHR (0.46) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL11402880 1.00 TSHR (0.46) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL9067354 0.97 TSHR (0.43) TSHRALDH1A1LMNATHRBDNM1
SCHEMBL4898877 0.97
SCHEMBL2479083 0.89
SCHEMBL5404425 0.89
Ammonia Solution, Strong SCHEMBL9013083 0.86 TSHR (0.38) TSHRALDH1A1LMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113308290-B Flame-retardant transformer oil and preparation method thereof 清华大学 2022-09-09 CN claimed
CN-113308290-A Flame-retardant transformer oil and preparation method thereof 清华大学 2021-08-27 CN claimed
EP-1716145-B1 DIHYDROTETRABENAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CAMBRIDGE LAB IRELAND LTD (IE) 2008-08-27 EP claimed
US-5869737-A REACTING A MALONIC ACID DERIVATIVE AND A 1,2-DICHLORO COMPOUND WITH AN ALCOHOLATE; CYCLIZATION; SOLVENT EXTRACTION; DISTILLATION HUELS AKTIENGESELLSCHAFT (DE) 1999-02-09 US claimed
CN-119219824-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-119219840-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
US-12069936-B2 Electronic device and method for slot-die depositing layers of the same EMPA Eidgenössische Materialprüfungs-und Forschungsanstalt (CH) 2024-08-20 US disclosed
US-12063847-B2 Method for forming an organic element of an electronic device MERCK PATENT GMBH (DE) 2024-08-13 US disclosed
CN-116063345-B Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2024-08-06 CN disclosed
CN-116063626-B Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-110963898-B Method for producing aromatic aldehyde ketone by gas phase oxidation 中国石油化工股份有限公司 2024-04-09 CN disclosed
CN-110963896-B Method for producing aromatic aldehyde ketone through gas phase oxidation reaction 中国石油化工股份有限公司 2024-04-09 CN disclosed
EP-0000534-A1 Process for the preparation of vinyl oxiranes BAYER AG (DE) 1979-02-07 EP disclosed
EP-0000554-A1 Process for the preparation of oxiranes substituted by halogen alkyl BAYER AG (DE) 1979-02-07 EP disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3971680-A AROMATIC QUATERNARY AMMONIUM POLYMER THE SHERWIN-WILLIAMS COMPANY (US) 1976-07-27 US disclosed
US-3943110-A Fiber and film-forming nuclearly-halogenated poly(1,4-benzamides) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-03-09 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed