⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420467 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL4896810 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL1412105 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL19462782 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL2369634 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL11402880 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL9067354 | 0.95 | TSHR (0.43) | — | |
| SCHEMBL2479083 | 0.92 | — | — | |
| SCHEMBL5404425 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL9013083 | 0.89 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265875-A4 | PROCESS FOR PREPARING PURE CRYSTALLINE LORAZEPAM | TEVA PHARMA (IL) | 2003-07-09 | — | — | EP | claimed |
| EP-1265875-A2 | PROCESS FOR PREPARING PURE CRYSTALLINE LORAZEPAM | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2002-12-18 | — | — | EP | claimed |
| US-6350870-B2 | Process for preparing pure crystalline lorazepam | TEVA PHARMACEUTICAL INDUSTREIS, LTD. (IL) | 2002-02-26 | — | — | US | claimed |
| US-20010039340-A1 | Process for preparing pure crystalline lorazepam | TEVA PHARMACEUTICALS USA, INC. | 2001-11-08 | — | — | US | claimed |
| WO-2001066062-A2 | PROCESS FOR PREPARING PURE CRYSTALLINE LORAZEPAM | TEVA PHARMAQCEUTICAL INDUSTRIES LTD. (IL) | 2001-09-13 | — | — | WO | claimed |
| CN-119219824-A | Crosslinked polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119219840-A | Crosslinked polymer and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116063345-B | Phosphonic acid group monomer and preparation method thereof | 中国石油化工股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-116063626-B | Anti-calcium shrinkage and expansion agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116064016-B | Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116063345-A | Phosphonic acid group monomer and preparation method thereof | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063626-A | Anti-calcium shrinkage and expansion agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-0008112-A1 | Process for the preparation of glycidyl esters of aromatic polycarboxylic acids | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008111-A1 | Process for the preparation of glycidyl esters of cycloaliphatic polycarboxylic acids | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008115-A1 | Process for the preparation of glycidyl esters of fumaric acid | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0002710-A1 | Process for the preparation of 5-(oxiranylmethyl)-1.3-benzodioxole | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000534-A1 | Process for the preparation of vinyl oxiranes | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000535-A1 | Process for the preparation of vinyl oxiranes substituted by halogen | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| US-4043943-A | Process for producing a mixed oxide of vanadium and phosphorus having an improved intrinsic surface area | CHEVRON RESEARCH COMPANY (US) | 1977-08-23 | — | — | US | disclosed |